1-甲基-4-苯基乙炔苯合成路线 （共 165 条）
反应条件
1: dihydrogen peroxide / water; tetrahydrofuran / 2 h / 0 - 20 °C / |Inert atmosphere 2: potassium tert-butylate / tetrahydrofuran / 5 h / |Inert atmosphere; |Reflux 3: tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium(0) / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Peng, Lifen; Xu, Feng; Suzuma, Yoshinori; Orita, Akihiro; Otera, Junzo
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12802 - 12808
参考文献
Scardiglia; Roberts
Tetrahedron, 1958 , vol. 3, p. 197,204
反应条件
triethylsilane; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; water; copper(II) sulfate in toluene 24 h; Reflux; stereoselective reaction;
参考文献
Luo, Fang; Pan, Changduo; Wang, Wenhui; Ye, Zhishi; Cheng, Jiang
Tetrahedron, 2010 , vol. 66, # 6 p. 1399 - 1403
反应条件
1: With diiron nonacarbonyl; 4-bromooctafluorobutanetriethoxysilane; N,N'-diphenyl-1H-pyrrol-2-amine-2-diphenylphosphane in tetrahydrofuran T=60°C; 12 h; 2: With sodium hydroxide in tetrahydrofuran; water T=20°C; 1 h;
参考文献
Enthaler, Stephan; Haberberger, Michael; Irran, Elisabeth
Chemistry - An Asian Journal, 2011 , vol. 6, # 6 p. 1613 - 1623
反应条件
palladium dichloride in chlorobenzene 10 h; Reflux; Overall yield = 80 percent;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
oxygen; palladium diacetate; zinc(II) chloride T=100°C; P=5700.38 Torr; 24 h;
参考文献
Wang, Azhong; Jiang, Huanfeng
Journal of the American Chemical Society, 2008 , vol. 130, # 15 p. 5030 - 5031
参考文献
Ghosh,K.; Bhattacharya,A.J.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1977 , vol. 15B, p. 678 - 680
反应条件
silver hexafluoroantimonate; bis-(phenyl)-sulfoxide; gold(I) chloride in 1,2-dichloro-ethane 3 h; Reflux;
参考文献
Xu, Cheng-Fu; Xu, Mei; Jia, Yi-Xia; Li, Chuan-Ying
Organic Letters, 2011 , vol. 13, # 6 p. 1556 - 1559
反应条件
[RuCl2(PPh3)4] in dichloromethane T=20°C;
参考文献
Allergan, Inc.
Patent: US2008/64872 A1, 2008 ;
Location in patent: Page/Page column 17 ;
US 20080064872 A1
反应条件
anhydrous lithium nitrate in water; acetonitrile Electrochemical reaction;
参考文献
Australian Journal of Chemistry, , vol. 60, # 6 p. 420 - 428
