1-甲基-4-苯基乙炔苯合成路线 （共 165 条）
反应条件
pyrrolidine; [(N-di(2-pyridyl)methyl-N'-cyclohexylurea)PdCl2]; tetrabutylammomium bromide in water T=100°C; Sonogashira-Hagihara reaction; 50 h;
参考文献
Najera, Carmen; Gil-Molto, Juan; Karlstroem, Sofia; Falvello, Larry R.
Organic Letters, 2003 , vol. 5, # 9 p. 1451 - 1454
反应条件
n-butyl-magnesium chloride; sodium methylate; sodium; Ca(OH)2 in tetrahydrofuran T=0°C; 0.0916667 h; Inert atmosphereReflux;
参考文献
Jin, Guanyi; Zhang, Xuxue; Cao, Song
Organic Letters, 2013 , vol. 15, # 12 p. 3114 - 3117
反应条件
polymer supported palladium catalyst in N,N-dimethyl-formamide T=70°C; Stille coupling reaction; 8 h;
参考文献
Dell'Anna, Maria Michela; Lofu, Antonio; Mastrorilli, Piero; Mucciante, Vittoria; Nobile, Cosimo Francesco
Journal of Organometallic Chemistry, 2006 , vol. 691, # 1-2 p. 131 - 137
反应条件
methanol; tri-tert-butyl phosphine; palladium diacetate; potassium carbonate in N,N-dimethyl acetamide T=100°C; 2 h; Inert atmosphere; regioselective reaction;
参考文献
Sakai, Norio; Komatsu, Ryosuke; Uchida, Naoki; Ikeda, Reiko; Konakahara, Takeo
Organic Letters, 2010 , vol. 12, # 6 p. 1300 - 1303
反应条件
methanol; tri-tert-butyl phosphine; palladium diacetate; potassium carbonate in N,N-dimethyl acetamide T=100°C; 2 h; Inert atmosphere; regioselective reaction;
参考文献
Sakai, Norio; Komatsu, Ryosuke; Uchida, Naoki; Ikeda, Reiko; Konakahara, Takeo
Organic Letters, 2010 , vol. 12, # 6 p. 1300 - 1303
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; water T=20°C; 12 h;
参考文献
Pena-Lopez, Miguel; Sarandeses, Luis A.; Perez Sestelo, Jose
European Journal of Organic Chemistry, 2013 , # 13 p. 2545 - 2554
反应条件
tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride in tetrahydrofuran T=60°C; 3 h;
参考文献
Chang, Sukbok; Yang, Soon Ha; Lee, Phil Ho
Tetrahedron Letters, 2001 , vol. 42, # 29 p. 4833 - 4835
反应条件
triethylamine; AgCl; palladium dichloride in acetonitrile T=20°C; Sonogashira coupling; 0.25 h;
参考文献
Zhu, Min; Zhou, Zhongshi; Chen, Rui
Synthesis, 2008 , # 17 art. no. P04108SS, p. 2680 - 2682
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; silver fluoride; sodium hydrogencarbonate in acetonitrile T=20°C; 3 h;
参考文献
Ye, Zhishi; Liu, Miaochang; Lin, Baoda; Wu, Huayue; Ding, Jinchang; Cheng, Jiang
Tetrahedron Letters, 2009 , vol. 50, # 5 p. 530 - 532
反应条件
bis-triphenylphosphine-palladium(II) chloride; oxygen in 1,4-dioxane T=80°C; Sonogashira type coupling; 18 h;
参考文献
Wang, Xuan; Qin, Weiwei; Kakusawa, Naoki; Yasuike, Shuji; Kurita, Jyoji
Tetrahedron Letters, 2009 , vol. 50, # 46 p. 6293 - 6297
