2-(溴乙酰基)-1,3-噻唑合成路线 （共 6 条）
反应条件
phenyltrimethylammonium bromide dibromide in tetrahydrofuran; dichloromethane
参考文献
Zambon Group S.p.A.
Patent: US6468979 B1, 2002 ;
反应条件
1: 1,3-thiazole With n-butyllithium in hexanes; diethyl ether T=-78°C; 0.25 h; 2: bromoacetic acid methyl ester in hexanes; diethyl ether T=-78 - 20°C;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/4117 A1, 2008 ;
Location in patent: Page/Page column 82-83 ;
反应条件
n-butyllithium in diethyl ether; hexane T=-30°C; 2 h;
参考文献
Dondoni, Alessandro; Marra, Alberto; Merino, Pedro
Journal of the American Chemical Society, 1994 , vol. 116, # 8 p. 3324 - 3336
反应条件
in dichloromethane 3 h; Ambient temperature;
参考文献
Dondoni, Alessandro; Marra, Alberto; Merino, Pedro
Journal of the American Chemical Society, 1994 , vol. 116, # 8 p. 3324 - 3336
反应条件
1: ZnCl2 / 180 °C 2: CHCl3; ozone / folgendes Erwaermen mit H2O 3: CCl4; bromine View Scheme
参考文献
Helvetica Chimica Acta, , vol. 31, p. 1142,1156
反应条件
1: acetic acid; aqueous Na2Cr2O7 2: CCl4; bromine View Scheme
参考文献
Helvetica Chimica Acta, , vol. 31, p. 1142,1156
