8-苄基-2,8-二氮杂-螺[4,5]葵烷合成路线 （共 13 条）
反应条件
1: NaOH / dioxane 2: H2 / Pd(OH)2/C / methanol / 5171.48 Torr View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 7 p. 1103 - 1107
反应条件
1: With triethylamine in dichloromethane T=0°C; 0.5 h; 2: With sodium tris(acetoxy)borohydride in dichloromethane T=20°C;
参考文献
NEUROGEN CORPORATION
Patent: WO2007/140383 A2, 2007 ;
Location in patent: Page/Page column 54-55 ;
WO 2007/140383 A2
反应条件
pyridine
T=20°C; 2 h;
参考文献
Naidu, B. Narasimhulu; Sorenson, Margaret E.
Patent: US2005/261322 A1, 2005 ;
Location in patent: Page/Page column 24 ;
