6,7-二甲氧基-3,4-二氢异喹啉合成路线 （共 75 条）
参考文献
Pelletier, Jeffrey C.; Cava, Michael P.
Synthesis, 1987 , # 5 p. 474 - 477
反应条件
1: 30 percent / 10 percent Pd/C / decahydronaphthalene / 1.5 h / 190 °C 2: 93 percent / 1 h / Heating View Scheme
参考文献
Langhals, Elke; Langhals, Heinz; Ruechardt, Christoph
Chemische Berichte, 1984 , vol. 117, # 4 p. 1436 - 1454
反应条件
1: palladium/charcoal; decalin 2: H2O View Scheme
参考文献
Popp; McEwen
Journal of the American Chemical Society, 1957 , vol. 79, p. 3773,3775
参考文献
Sugasawa; Kakemi
Chemische Berichte, 1939 , vol. 72, p. 980,983
Yakugaku Zasshi, 1940 , vol. 60, p. 6,9, 10
反应条件
in tetrahydrofuran 60 h; Ambient temperature; Further byproducts given;
参考文献
Grigg, R.; Gunaratne, H. Q. Nimal; Henderson, Deirdre; Sridharan, Visuvanathar
Tetrahedron, 1990 , vol. 46, # 5 p. 1599 - 1610
反应条件
1: 89 percent / toluene / 2 h / Heating 2: 76 percent / aq. KOH / acetonitrile; H2O / 3 h / 20 °C 3: 71 percent / aq. silver nitrate / acetonitrile; H2O / 16 h / 20 °C 4: 95 percent / Na; liq. NH3 / tetrahydrofuran / 0.5 h / -78 °C 5: 98 percent / Me3SiCl; NaI / acetonitrile / 24 h / 20 °C View Scheme
参考文献
Pauvert, Mickael; Collet, Sylvain; Guingant, Andre
Tetrahedron Letters, 2003 , vol. 44, # 22 p. 4203 - 4206
反应条件
hydrogenchloride in methanol; water T=0 - 20°C; 17 h;
参考文献
Imbri, Dennis; Tauber, Johannes; Opatz, Till
Chemistry - A European Journal, 2013 , vol. 19, # 45 p. 15080 - 15083
反应条件
hydrogenchloride in methanol T=0 - 20°C;
参考文献
Werner, Frank; Blank, Nancy; Opatz, Till
European Journal of Organic Chemistry, 2007 , # 23 p. 3911 - 3915
反应条件
Jacobsen catalyst in methanol; toluene T=-70°C; Strecker reaction; 40 h;
参考文献
Kanemitsu, Takuya; Yamashita, Yuki; Nagata, Kazuhiro; Itoh, Takashi
Synlett, 2006 , # 10 p. 1595 - 1597
反应条件
1: 89 percent / benzene / 24 h / Ambient temperature
2: 98 percent / n-BuLi / tetrahydrofuran; hexane / 1.) -35 deg C, 30 min, 2.) -30 deg C, 3 h
3: 90 percent / conc. hydrochloric acud / Heating
4: 68 percent / 1.) 10 percent acetic acid, sodium acetate, 2.) NaI / 0.25 h / Heating
View Scheme
参考文献
Kiparissides, Zinovia; Fichtner, Robert H.; Poplawski, Janusz; Nalliah, Bala C.; MacLean, David B.
Canadian Journal of Chemistry, 1980 , vol. 58, p. 2770 - 2779
