2-(甲基硫代)-5,6,7,8-四氢喹唑啉-4(3h)-酮合成路线 (共 5 条)
反应条件
1: 67 percent / pyrrolidine / 7 h / 150 °C / in a sealed tube 2: 64 percent / isoamyl nitrite / trifluoroacetic acid; CHCl3 / 3 h / Heating View Scheme
参考文献
MERCK PATENT GMBH; BUCHSTALLER, Hans-Peter; ESDAR, Chirstina; LEUTHNER, Birgitta
Patent: WO2013/117288 A1, 2013 ;
反应条件
1: sodium methylate; methanol View Scheme
参考文献
Curd; Rose
Journal of the Chemical Society, 1946 , p. 362,365
参考文献
Brady; Herbst
Journal of Organic Chemistry, 1959 , vol. 24, p. 922,924
Full Text Show Details
Curd; Rose
Journal of the Chemical Society, 1946 , p. 362,365
参考文献
Curd; Rose
Journal of the Chemical Society, 1946 , p. 362,365
反应条件
trichlorophosphate
T=110°C;
参考文献
Smithkline Beecham corporation
Patent: WO2003/101442 A1, 2003 ;
Location in patent: Page 55 ;
WO 03/101442 A1