1,1,1,2-四甲氧基乙烷合成路线 （共 5 条）
反应条件
1: 2-methoxyacetonitrile With hydrogenchloride in methanol; diethyl ether T=-15 - 20°C; 20.33 h; 2: methanol in diethyl ether 25.5 h; Heating / reflux;
参考文献
PFIZER LIMITED
Patent: WO2006/123242 A1, 2006 ;
Location in patent: Page/Page column 44 ;
WO 2006/123242 A1
反应条件
1: With hydrogenchloride in methanol T=0 - 20°C; 20 h; 2: in methanol 6 h; Heating / reflux;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2005/28452 A1, 2005 ;
Location in patent: Page/Page column 83 ;
WO 2005/028452 A1
反应条件
in pentane 72 h; Ambient temperature;
参考文献
Bakker, C. G.; Scheeren, J. W.; Nivard, R. J. F.
Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 1 p. 13 - 20
反应条件
in hydrogenchloride T=25°C; Thermodynamic data;
参考文献
Guthrie, J.Peter; Cullimore, Patricia A.
Canadian Journal of Chemistry, 1980 , vol. 58, p. 1281 - 1294
反应条件
Al tri-t-BuO-
4 h; Heating;
参考文献
Bakker, C. G.; Scheeren, J. W.; Nivard, R. J. F.
Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 1 p. 13 - 20
