2-(三氟甲基)乙酰苯胺合成路线 （共 23 条）
反应条件
[DBU][HOAc] in neat (no solvent) T=50°C; 0.5 h; Green chemistry;
参考文献
Ji, Li; Qian, Chao; Chen, Xin-Zhi
Monatshefte fur Chemie, 2013 , vol. 144, # 3 p. 369 - 374
反应条件
triethylamine in chloroform T=23°C; 1 h;
参考文献
Strekowski; Patterson; Janda; Wydra; Harden; Lipowska; Cegla
Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 196 - 201
反应条件
copper diacetate; 2,2,2-trimethylacetic acid in 1,2-dichloro-ethane T=110°C; 12 h; Inert atmosphereSchlenk techniqueSealed tube;
参考文献
Zhang, Li-Sheng; Chen, Kang; Chen, Guihua; Li, Bi-Jie; Luo, Shuang; Guo, Qing-Yun; Wei, Jiang-Bo; Shi, Zhang-Jie
Organic Letters, 2013 , vol. 15, # 1 p. 10 - 13
反应条件
copper diacetate; palladium diacetate; 2,2,2-trimethylacetic acid in 1,2-dichloro-ethane T=110°C; 24 h; Inert atmosphereSchlenk techniqueSealed tubeGreen chemistry; Catalytic behavior; Reagent/catalystConcentrationSolvent;
参考文献
Zhang, Li-Sheng; Chen, Kang; Chen, Guihua; Li, Bi-Jie; Luo, Shuang; Guo, Qing-Yun; Wei, Jiang-Bo; Shi, Zhang-Jie
Organic Letters, 2013 , vol. 15, # 1 p. 10 - 13
反应条件
(i) H2, Raney-Ni, EtOH, (ii) (acetylation); Multistep reaction;
参考文献
Tetrahedron, , vol. 18, p. 1369 - 1376
反应条件
1: toluene / 1 h / 120 °C / |Sealed tube; |Inert atmosphere 2: copper diacetate; 2,2,2-trimethylacetic acid / 1,2-dichloro-ethane / 12 h / 110 °C / |Inert atmosphere; |Schlenk technique; |Sealed tube View Scheme
参考文献
Organic Letters, , vol. 15, # 1 p. 10 - 13
反应条件
1: sulfuric acid; nitric acid / und Erwaermen des Reaktionsprodukts mit aethanol.Natronlauge 2: ethanol; concentrated H2SO4 / 0 - 10 °C / Erwaermen der Reaktionsloesung mit Kupferbronze 3: palladium / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 69, p. 2352
反应条件
1: ethanol; concentrated H2SO4 / 0 - 10 °C / Erwaermen der Reaktionsloesung mit Kupferbronze 2: palladium / Hydrogenation View Scheme
参考文献
Journal of the American Chemical Society, , vol. 69, p. 2352
反应条件
lithium diisopropyl amide in tetrahydrofuran 1.) -50 deg C, 2.) -78 deg C, 1h; -78 to 23 deg C, 1 h; 23 deg C, 2 h; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 59, # 20 p. 5886 - 5890
反应条件
[bis(acetoxy)iodo]benzene; silver fluoride in dimethyl sulfoxide T=20°C; 20 h;
参考文献
Chemical Communications, , vol. 49, # 57 p. 6385 - 6387
