1.1: sulfuric acid / N,N-dimethyl-formamide / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide 2.2: 4 h / 20 °C 3.1: hydrogenchloride; water / methanol / 4 h / 20 °C 4.1: sodium periodate / ethanol; water; methanol / 3 h / 20 °C 5.1: copper(II) bis(trifluoromethanesulfonate); borane-THF / 2 h / 20 °C / |Inert atmosphere 6.1: 1H-imidazole; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 24 h / 20 °C / |Inert atmosphere 7.1: pyridine / dichloromethane / 1 h / -15 °C / |Inert atmosphere 8.1: sodium azide / N,N-dimethyl-formamide / 2 h / 20 °C 9.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 9.2: 4 h / 20 °C 10.1: pyridine / 2 h / 0 - 20 °C 11.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere 12.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 12.2: 0.75 h / -78 - 20 °C / |Inert atmosphere 13.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 13.2: 2 h / 0 °C / |Inert atmosphere 14.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 15.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 16.1: triethylamine / dichloromethane / 0.75 h / 0 °C 17.1: sodium azide / ethanol; water / 8 h / |Reflux 18.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 18.2: Staudinger Azide Reduction / 24 h / 20 °C View Scheme

hydrogen in water T=244.84°C; P=45004.5 Torr; 3 h;

sulfuric acid in water T=190°C; 0.833333 h; TimeTemperatureConcentration;

暂无反应条件数据

1: 83 percent / acetyl chloride / 50 deg C for 1.5 h then room temperature for 24 h 2: 89 percent / imidazole / dimethylformamide / 6 h / Ambient temperature 3: 97 percent / camphorsulphonic acid / acetone / 16 h / Ambient temperature 4: pyridinium chlorochromate, molecular sieve 3 A / CH2Cl2 / 2 h / Ambient temperature; molecular sieve 3 A 5: sodium borohydride / ethanol / 1 h / 0 °C 6: pyridine / CH2Cl2 / 8 h / -20 °C 7: sodium azide / dimethylformamide / 16 h / Ambient temperature 8: 97 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / Ambient temperature 9: 100 percent / hydrogen / palladium black / methanol / 1 h / Ambient temperature 10: aq. sodium bicarbonate / diethyl ether / 1.5 h / 0 °C 11: 75 percent / pyridinium chlorochromate, molecular sieve 3 A / CH2Cl2 / 1.5 h / Ambient temperature 12: 59 percent / CH2Cl2 / 16 h / Ambient temperature 13: 61 percent / hydrogen / palladium black / methanol / 48 h 14: H2 / palladium black / acetic acid / 72 h / Ambient temperature 15: 74 percent / trifluoroacetic acid / D2O / 50 h / Ambient temperature View Scheme

chromium dichloride T=120°C; 3 h; Inert atmosphereIonic liquid; Reagent/catalyst;

water T=200°C; Kinetics;

hydrogen in water T=244.84°C; P=45004.5 Torr; 3 h;

暂无反应条件数据

hydroxide zinc; ammonia