1,3,6,8-四(叔丁基)咔唑合成路线 （共 5 条）
反应条件
hydrogenchloride; aluminium trichloride T=20°C; Friedel-Crafts alkylation; 24 h;
参考文献
Mudadu, Maria S.; Singh, Ajay N.; Thummel, Randolph P.
Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6513 - 6520
反应条件
aluminium trichloride
参考文献
Kuhn, Norbert; Schulten, Michael; Boese, Roland; Blaeser, Dieter
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1991 , vol. 46, # 11 p. 1503 - 1508
反应条件
trifluoroacetic acid Heating;
参考文献
Moskalev, N. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1990 , vol. 26, # 2 p. 158 - 160
Khimiya Geterotsiklicheskikh Soedinenii, 1990 , vol. 26, # 2 p. 187 - 189
反应条件
potassium hydroxide; diethylaluminium chloride 1.) heptane, reflux, 30 min, 2.) 20 degC, 1 h; Yield given. Multistep reaction;
参考文献
Kuznetsov, V. L.; Lopatinskii, V. P.; Filimonov, V. D.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 10 p. 1988 - 1991
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 10 p. 2214 - 2217
反应条件
sulfuric acid T=20°C; 24 h;
参考文献
Mudadu, Maria S.; Singh, Ajay N.; Thummel, Randolph P.
Journal of Organic Chemistry, 2008 , vol. 73, # 17 p. 6513 - 6520
