1: piperidine With hydrogenchloride in water; butan-1-ol T=0°C; 0.5 h; 2: sodium dicyanoamide in water; butan-1-ol 24 h; Reflux;
参考文献
HANALL BIOPHARMA CO., LTD.; KIM, Sung Wuk; MIN, Chang Hee; PARK, Se Hwan; KIM, Duck; LEE, Ji Sun; KIM, Yong Eun; OH, Ju Hoon
Patent: WO2013/22278 A2, 2013 ;
Location in patent: Paragraph 101-103 ;
WO 2013/022278 A2
