反应条件
1: With (trans)-1,2-cyclohexanedicarboxylic acid; (1S,2S)-1,2-diaminocyclohexane in isopropyl alcohol T=0°C; Robinson type asymmetric annulation; 8 h; 2: With tetra(n-butyl)ammonium hydroxide; potassium hydroxide in tetrahydrofuran; diethyl ether; water; isopropyl alcohol T=60°C; Robinson type asymmetric annulation; 0.5 h; optical yield given as percent ee;
参考文献
Lnokoishi, Yogo; Sasakura, Niiha; Nakano, Keiji; Ichikawa, Yoshiyasu; Kotsuki, Hiyoshizo
Organic Letters, 2010 , vol. 12, # 7 p. 1616 - 1619
