tert.-butylnitrite; ascorbic acid powder in dimethyl sulfoxide; acetonitrile T=20°C; 12 h; Inert atmosphereGreen chemistry; regioselective reaction;

lithium hydroxide; caesium carbonate; potassium iodide; Merrifield resin; tetrakis(triphenylphosphine) palladium(0) 1.) DMF, 80 deg C, 16 h; 2.) DMF, 60 degC, 24 h; 3.) THF, MeOH, H2O, reflux, 18 h; Yield given. Multistep reaction;