顺式-9-十八碳烯基甲烷磺酸酯合成路线 （共 15 条）
反应条件
triethylamine in dichloromethane T=20°C; Esterification;
参考文献
Meekel, Arthur A. P.; Wagenaar, Anno; Smisterova, Jarmila; Kroeze, Jessica E.; Haadsma, Peter; Bosgraaf, Bouke; Stuart, Marc C. A.; Brisson, Alain; Ruiters, Marcel H. J.; Hoekstra, Dick; Engberts, Jan B. F. N.
European Journal of Organic Chemistry, 2000 , # 4 p. 665 - 673
反应条件
sodium hydrogencarbonate in pyridine; ethanol; chloroform; water; methanesulfonyl chloride
参考文献
Vical, Inc.
Patent: US5264618 A1, 1993 ;
反应条件
pyridine in ice-water; dichloromethane
参考文献
Megabios Corporation
Patent: US6121457 A1, 2000 ;
反应条件
1: LiAlH4 2: 96 percent / triethylamine / CH2Cl2 / 20 °C View Scheme
参考文献
Bascetta, Emanuele; Gunstone, Frank D.; Walton, John C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , p. 603 - 614
反应条件
(i) K, benzene, (ii) /BRN= 1913855/, (iii) aq. HCl, MeOH; Multistep reaction;
参考文献
Baumann,W.J.; Mangold,H.K.
Journal of Organic Chemistry, 1964 , vol. 29, p. 3055 - 3057
反应条件
1.1: KOH / toluene / 3 h / Heating 1.2: toluene / 6 h / Heating 2.1: 9.8 g / aq. HCl / methanol / 2 h / 80 °C View Scheme
参考文献
Joll, Cynthia A.; Mortimer, Bok-Cheng; Redgrave, Trevor G.; Stick, Robert V.
Australian Journal of Chemistry, 1990 , vol. 43, # 8 p. 1445 - 1448
反应条件
1: MsO-oleyl With potassium hydroxide; water in methanol T=55°C; 1.5 h; 2: methanol With sulfuric acid in water T=20 - 55°C; 1.5 h;
参考文献
WASHINGTON STATE UNIVERSITY
Patent: WO2008/86495 A1, 2008 ;
Location in patent: Page/Page column 18; 23; 30 ;
反应条件
lithium bromide in acetone Bromination; 3 h; Heating;
参考文献
Meekel, Arthur A. P.; Wagenaar, Anno; Smisterova, Jarmila; Kroeze, Jessica E.; Haadsma, Peter; Bosgraaf, Bouke; Stuart, Marc C. A.; Brisson, Alain; Ruiters, Marcel H. J.; Hoekstra, Dick; Engberts, Jan B. F. N.
European Journal of Organic Chemistry, 2000 , # 4 p. 665 - 673
反应条件
potassium hydroxide in anhydrous xylene; ethyl acetate
反应条件
1: 1.) KOH / 1.) xylene, 1h, reflux; 2.) xylene, 5h, reflux 2: HCl/methanol / 1 h / Heating View Scheme
参考文献
Alunni-Bistocchi; Orvietani; Ricci; Binaglia; Orlando
Farmaco, 1990 , vol. 45, # 5 p. 499 - 509
