2,2′-联吡啶-3,3′-二醇合成路线 （共 18 条）
反应条件
nickel; triphenylphosphine; zinc in N,N-dimethyl-formamide T=50°C; 3 h;
参考文献
Naumann, Christoph; Langhals, Heinz
Synthesis, 1990 , # 4 p. 279 - 281
反应条件
pyridine hydrochloride 4 h; Heating;
参考文献
Dehmlow, Eckehard V.; Sleegers, Arthur
Liebigs Annalen der Chemie, 1992 , # 9 p. 953 - 960
反应条件
iodine; copper in N,N-dimethyl-formamide Heating;
参考文献
Dehmlow, Eckehard V.; Schulz, Hans-Joachim
Journal of Chemical Research, Miniprint, 1987 , # 11 p. 2951 - 2973
反应条件
ammonium chloride in methanol T=210°C; 2 h;
参考文献
Langhals, Heinz; Pust, Stefan
Chemische Berichte, 1985 , vol. 118, # 12 p. 4674 - 4681
反应条件
1: 64.8 percent / Ni(0)-PPh3 2: 78 percent / 33percent HBr / acetic acid / 4 h / Heating View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 11 p. 2951 - 2973
反应条件
1: CuBr; [Pd(PPh3)4] / dioxane / 15 h / Heating 2: aq. HCl / diethyl ether / 15 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 58, # 2 p. 309 - 314
反应条件
ammonium acetate T=150°C; 2 h; Yields of byproduct given;
参考文献
Siemanowski, Werner; Witzel, Herbert
Liebigs Annalen der Chemie, 1984 , # 10 p. 1731 - 1739
反应条件
1: 1.) n-C4H9Li / 1.) ether, n-hexane, -65 deg C; 2.) ether, 4h, from -65 deg C to 20 deg C 2: 1 N HCl / H2O / 2 h / 60 °C 3: 62 percent / ammonium acetate / 2 h / 150 °C 4: 48 percent HBr / acetic acid / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1731 - 1739
反应条件
1: 1.) n-C4H9Li / 1.) ether, 3 h, reflux; 2.) ether, 4 h, from -60 deg C to 10 deg C 2: 1 N HCl / H2O / 2 h / 60 °C 3: 62 percent / ammonium acetate / 2 h / 150 °C 4: 48 percent HBr / acetic acid / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1731 - 1739
反应条件
hydrogen bromide in acetic acid Heating; Yield given;
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1731 - 1739
