4-氨基-5-吡啶-4H-三唑硫醇合成路线 （共 10 条）
反应条件
1: With potassium hydroxide in ethanol T=20°C; 12 h; 2: With hydrazine hydrate in water 6 h; Reflux; 3: With hydrogenchloride in water Cooling;
参考文献
Cheeseright, Timothy J.; Holm, Melanie; Lehmann, Frank; Luik, Sabine; Gottert, Marcia; Melville, James L.; Laufer, Stefan
Journal of Medicinal Chemistry, 2009 , vol. 52, # 14 p. 4200 - 4209
反应条件
hydrazine hydrate T=140 - 160°C; 6 h;
参考文献
Mobinikhaledi, Akbar; Foroughifar, Naser; Bayat, Mahsa
Organic Preparations and Procedures International, 2011 , vol. 43, # 4 p. 368 - 371
反应条件
1: KOH / ethanol / 14 h 2: hydrazine hydrate / H2O / Heating View Scheme
参考文献
Heterocycles, , vol. 68, # 9 p. 1901 - 1907
反应条件
hydrazine hydrate 0.133333 h; microwave irradiation;
参考文献
Joshi; Karnik
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 4 p. 1057 - 1059
反应条件
1.1: H2SO4 2.1: H2NNH2*H2O 3.1: KOH 3.2: H2NNH2*H2O / 120 °C View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 181, # 9 p. 2079 - 2087
反应条件
1.1: H2NNH2*H2O 2.1: KOH 2.2: H2NNH2*H2O / 120 °C View Scheme
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 181, # 9 p. 2079 - 2087
反应条件
1.1: hydrazine hydrate / Reflux 2.1: potassium hydroxide / methanol / 0.25 h 2.2: 3 h / 20 - 25 °C 3.1: hydrazine hydrate / water / 1 h / Reflux View Scheme
参考文献
Arzneimittel-Forschung/Drug Research, , vol. 61, # 8 p. 452 - 457
参考文献
Hassan
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 11 p. 2759 - 2776
反应条件
trichlorophosphate 5 h; Heating;
参考文献
Invidiata; Grimaudo; Giammanco
Farmaco, 1991 , vol. 46, # 12 p. 1489 - 1495
反应条件
trichlorophosphate 5 h; Reflux;
参考文献
Hussein, Mostafa A.; Shaker, Refaat M.; Ameen, Mohammed A.; Mohammed, Mohammed F.
Archives of Pharmacal Research, 2011 , vol. 34, # 8 p. 1239 - 1250
