5-(2-溴-乙酰基)-2-羟基-苯甲酸甲酯合成路线 （共 6 条）
反应条件
bromine in chloroform
参考文献
Grisar; Claxton; Bare; Dage; Cheng; Woodward
Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 327 - 336
反应条件
1: 96 percent / H2SO4 / 24 h / Heating 2: 76 percent / dioxane dibromide / dioxane; diethyl ether / 2 h / Ambient temperature View Scheme
参考文献
Leclerc, Gerard; Bizec, Jean Claude; Bieth, Nicole; Schwartz, Jean
Journal of Medicinal Chemistry, 1980 , vol. 23, # 7 p. 738 - 744
反应条件
1: 82 percent / AlCl3 / nitrobenzene / 1 h 2: 96 percent / H2SO4 / 24 h / Heating 3: 76 percent / dioxane dibromide / dioxane; diethyl ether / 2 h / Ambient temperature View Scheme
参考文献
Leclerc, Gerard; Bizec, Jean Claude; Bieth, Nicole; Schwartz, Jean
Journal of Medicinal Chemistry, 1980 , vol. 23, # 7 p. 738 - 744
反应条件
2: LiAlH4 3: H2 / Pd-C View Scheme
参考文献
Collin; Hartley; Jack; Lunts; Press; Ritchie; Toon
Journal of medicinal chemistry, 1970 , vol. 13, # 4 p. 674 - 680
反应条件
sodium formate; N-hexadecyl-N,N,N-trimethylammonium bromide; sodium lauryl sulfate; (R,R)-TsDPEN; [{(η5-C5Me5)RhCl}2(μ-Cl)2] in water T=28°C; 5 h; Title compound not separated from byproducts;
参考文献
Wang, Fei; Liu, Hui; Cun, Linfeng; Zhu, Jin; Deng, Jingen; Jiang, Yaozhong
Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9424 - 9429
反应条件
water; dimethyl sulfoxide
参考文献
Collin; Hartley; Jack; Lunts; Press; Ritchie; Toon
Journal of medicinal chemistry, 1970 , vol. 13, # 4 p. 674 - 680
