6-氯-1,2,3,4-四氢咔唑合成路线 （共 19 条）
反应条件
1,3-bis(3-sulfopropyl)-1H-imidazol-3-ium trifluoromethanesulfonate in water T=100°C; Fischer Indole Synthesis; 0.333333 h; Microwave irradiationGreen chemistry;
参考文献
Li, Bai Lin; Zhong, Ai Guo; Xu, Dan-Qian
Journal of Fluorine Chemistry, 2012 , vol. 144, p. 45 - 50,6
反应条件
L-(+)-tartaric acid-urea melt T=70°C; Fischer Indole Synthesis; 0.5 h;
参考文献
Gore, Sangram; Baskaran, Sundarababu; Koenig, Burkhard
Organic Letters, 2012 , vol. 14, # 17 p. 4568 - 4571
反应条件
toluene-4-sulfonic acid in ethanol Heating;
参考文献
Wagaw; Yang; Buchwald
Journal of the American Chemical Society, 1998 , vol. 120, # 26 p. 6621 - 6622
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in 1,4-dioxane T=180°C; 50 h;
参考文献
Tsuji, Yasushi; Huh, Keun-Tae; Watanabe, Yoshihisa
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1673 - 1680
反应条件
sodium acetate; iron; acetic acid in ethanol; water 2 h; Heating;
参考文献
RajanBabu, T. V.; Chenard, Bertrand L.; Petti, Michael A.
Journal of Organic Chemistry, 1986 , vol. 51, # 10 p. 1704 - 1712
反应条件
in cyclohexanone; acetic acid
参考文献
Mochida Pharmaceutical Co., Ltd.
Patent: US6018046 A1, 2000 ;
反应条件
1: 98 percent / Pd(OAc)2; Xantphos; t-BuONa / toluene / 1.5 h / 80 °C 2: 91 percent / p-TsOH*H2O / ethanol / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 44 p. 10251 - 10263
反应条件
in ethanol; cyclohexanone; ethyl acetate
反应条件
methyllithium in tetrahydrofuran -40 deg C, 1 h; r.t., overnight;
参考文献
Suzuki, Hideharu; Tsukuda, Akiko; Kondo, Mika; Aizawa, Miki; Senoo, Yumiko; et al.
Tetrahedron Letters, 1995 , vol. 36, # 10 p. 1671 - 1672
反应条件
in 2-ethoxy-ethanol Bischler reaction; 0.166667 h; microwave irradiation;
参考文献
Chen, Jing; Hu, Yongzhou
Synthetic Communications, 2006 , vol. 36, # 11 p. 1485 - 1494
