反应条件
1: hydrogenchloride / isopropyl alcohol / 2 h / Reflux 2: trifluoroacetic acid / 1 h / Reflux 3: potassium carbonate / N,N-dimethyl-formamide / 20 - 90 °C 4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C 5: NaBH(OAc)3; acetic acid / methanol; dichloromethane; water / 2 h / 20 °C View Scheme
参考文献
Gao, Mingzhang; Lola, Christian M.; Wang, Min; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3222 - 3226