1-噁螺[2.5]辛烷-2-甲腈合成路线 （共 9 条）
反应条件
diphenyl diselenide; sodium perchlorate; malonic acid dimethyl ester in methanol T=15 - 20°C; electrolysis with (Mg)-anode and (Pt)-cathode;
参考文献
Inokuchi, Tsutomu; Kusumoto, Masahiko; Sugimoto, Tatsuya; Tanaka, Hideo; Torii, Sigeru
Phosphorus, Sulfur and Silicon and the Related Elements, 1992 , vol. 67, # 1-4 p. 271 - 276
反应条件
boron trifluoride in diethyl ether
参考文献
Inokuchi, Tsutomu; Kusumoto, Masahiko; Matsumoto, Sigeaki; Okada, Hiroyuki; Torii, Sigeru
Chemistry Letters, 1991 , p. 2009 - 2012
反应条件
1: 86 percent / 70percent HF / CH2Cl2; pyridine / 1.) 0 deg C, 1 h, 2.) room temp., 1 h 2: 74 percent / NaBH4 / propan-2-ol; H2O / 1 h / 0 °C View Scheme
参考文献
Mongelli; Animati; D'Alessio; Zuliani; Gandolfi
Synthesis, 1988 , # 4 p. 310 - 313
反应条件
1: 86 percent / 70percent HF / CH2Cl2; pyridine / 1.) 0 deg C, 1 h, 2.) room temp., 1 h 2: 74 percent / NaBH4 / propan-2-ol; H2O / 1 h / 0 °C 3: 59 percent / Jones reagent / acetone / 0 °C View Scheme
参考文献
Mongelli; Animati; D'Alessio; Zuliani; Gandolfi
Synthesis, 1988 , # 4 p. 310 - 313
反应条件
sodium hydroxide in tetrahydrofuran
T=20 - 30°C; Darzens condensation; 0.416667 h;
参考文献
Jonczyk; Gadaj
Polish Journal of Chemistry, 2007 , vol. 81, # 9 p. 1595 - 1610
反应条件
1: HCl / diethyl ether
2: aq. NaOH
View Scheme
参考文献
Stork,G. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 4315 - 4323
反应条件
1: 30 percent / ZnCl2 / benzene / 0.5 h / Heating
2: 56 percent / Et3N / toluene / 9 h / Heating
View Scheme
参考文献
Zdrojewski; Fedorynski; Jonczyk
Polish Journal of Chemistry, 1997 , vol. 71, # 7 p. 941 - 946
反应条件
1: HCl / diethyl ether
2: aq. NaOH / ethanol
View Scheme
参考文献
Stork,G. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 4315 - 4323
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Stork,G. et al.
Journal of the American Chemical Society, 1960 , vol. 82, p. 4315 - 4323
