6-甲基-2-(邻苯二甲酰亚氨基)吡啶合成路线 （共 7 条）
反应条件
1: 62 percent / NBS / H2O; CCl4 2: NaI / ethanol / 15 h / Heating 3: hydrazine hydrate View Scheme
参考文献
Goswami; Ghosh; Mukherjee; Avijit Kumar Adak; Ajit Kumar Mahapatra
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 1 p. 173 - 178
参考文献
ASTRAZENECA AB; ASTEX THERAPEUTICS
Patent: WO2006/65204 A1, 2006 ;
Location in patent: Page/Page column 140 ;
WO 2006/065204 A1
反应条件
1: 60 percent / glacial acetic acid / acetic acid / 4 h / Heating
2: 55 percent / 10percent aq. NaOH / 2 h
View Scheme
参考文献
Abdel-Aziz
Pakistan Journal of Scientific and Industrial Research, 1996 , vol. 39, # 5-8 p. 122 - 127
反应条件
1: 60 percent / glacial acetic acid / acetic acid / 4 h / Heating
2: 55 percent / 10percent aq. NaOH / 2 h
View Scheme
参考文献
Abdel-Aziz
Pakistan Journal of Scientific and Industrial Research, 1996 , vol. 39, # 5-8 p. 122 - 127
反应条件
N-bromosuccinmide in tetrachloromethane; water
参考文献
Goswami; Ghosh; Mukherjee; Avijit Kumar Adak; Ajit Kumar Mahapatra
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 1 p. 173 - 178
反应条件
dibenzoyl peroxide in tetrachloromethane
参考文献
Merck and Co., Inc.
Patent: US4490533 A1, 1984 ;
反应条件
N-bromosuccinmide
0.15 h; microwave irradiation;
参考文献
Goswami, Shyamaprosad; Dey, Swapan; Jana, Subrata; Adak, Avijit Kumar
Chemistry Letters, 2004 , vol. 33, # 7 p. 916 - 917
