2(S)-氨基-3-(3,4-二羟基苯基)丙酸乙酯合成路线 （共 3 条）
反应条件
water; sodium chloride in dimethyl sulfoxide T=37°C; also human plasma as reagent; Rate constant;
参考文献
Brunner-Guenat; Carrupt; Lisa; Testa; Rose; Thomas; Jenner; Ventura
Journal of Pharmacy and Pharmacology, 1995 , vol. 47, # 10 p. 861 - 869
反应条件
thionyl chloride; 2,6-di-tert-butyl-4-methyl-phenol; sodium hydrogencarbonate; sodium sulfate in ethanol; water
参考文献
Yissum Research Development Company of the Hebrew University of Jerusalem; Teva Pharmaceutical Industries Ltd.
Patent: US5607969 A1, 1997 ;
反应条件
hydrogenchloride
Fischer esterification;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; SATYAMURTHY, Nagichettiar; BARRIO, Jorge, R.
Patent: WO2010/117435 A2, 2010 ;
Location in patent: Page/Page column 18 ;
