N-苯基双(三氟甲烷磺酰)亚胺合成路线 （共 107 条）
反应条件
triethylamine in dichloromethane T=0 - 20°C; 2.5 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/94822 A1, 2005 ;
Location in patent: Page/Page column 37 ;
WO 2005/094822 A1
反应条件
triethylamine in dichloromethane 4 h;
参考文献
Jacobsen, Eric Jon; Myers, Jason K.; Walker, Daniel Patrick; Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Acker, Brad A.; Groppi JR., Vincent E.
Patent: US2003/236270 A1, 2003 ;
Location in patent: Page 38 ;
反应条件
1: 1,2,3,4-tetrahydro-naphthalen-2-one With potassium tert-butylate in tetrahydrofuran T=-20 - 0°C; 1.16667 h; 2: N,N-bis(trifluoromethanesulfonyl)aniline in tetrahydrofuran T=-20 - 0°C; 4.01667 h; Inert atmosphere;
参考文献
Konishi, Hideyuki; Ueda, Tsuyoshi; Manabe, Kei
Organic Syntheses, 2014 , vol. 91, p. 39 - 51
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C; 16 h;
参考文献
The Regents of the University of California
Patent: US2011/312905 A1, 2011 ;
Location in patent: Page/Page column 40 ;
反应条件
potassium carbonate in tetrahydrofuran T=120°C; 0.133333 h; Microwave irradiation;
参考文献
Heim, Ralf; Lucas, Simon; Grombein, Cornelia M.; Ries, Christina; Schewe, Katarzyna E.; Negri, Matthias; Mueller-Vieira, Ursula; Birk, Barbara; Hartmann, Rolf W.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 16 p. 5064 - 5074
反应条件
potassium carbonate in tetrahydrofuran T=120°C; 0.1 h; microwave heating;
参考文献
Bengtson, Anna; Hallberg, Anders; Larhed, Mats
Organic Letters, 2002 , vol. 4, # 7 p. 1231 - 1233
反应条件
sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide 1.) 0 deg C, 30 min, 2.) r.t., 30 min;
参考文献
Yamano, Yumiko; Mimuro, Mamoru; Ito, Masayoshi
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 18 p. 2713 - 2724
反应条件
sodium hydride Multistep reaction;
参考文献
Houpis, Ioannis N.
Tetrahedron Letters, 1991 , vol. 32, # 46 p. 6675 - 6678
反应条件
potassium hexamethylsilazane in tetrahydrofuran; toluene T=-78°C; 4 h;
参考文献
Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh
Patent: US2008/300242 A1, 2008 ;
Location in patent: Page/Page column 102 ;
US 20080300242 A1
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Inert atmosphere;
参考文献
Xiang, Zheng; Wang, Lei
Journal of Organic Chemistry, 2011 , vol. 76, # 15 p. 6367 - 6371
