(S)-2-苯基-1-丙醇合成路线 （共 88 条）
反应条件
1: With (R,R)-(-)-[N,N(1)-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminoat(2-)]manganese (III) chloride Inert atmosphere; 2: With C12H6F18Fe3O16 in dichloromethane T=20°C; 3 h; Inert atmosphere; 3: With methanol; sodium tetrahydroborate optical yield given as percent eeenantioselective reaction;
参考文献
Zhuang, Minyang; Du, Haifeng
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 9 p. 1460 - 1462
反应条件
butan-1-ol in hexane; water T=30°C; porcine pancreatic lipase (PPL); Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chen, Ching-Shih; Liu, Yeuk-Chuen
Journal of Organic Chemistry, 1991 , vol. 56, # 5 p. 1966 - 1968
反应条件
horse liver alcohol dehydrogenase and nicotinamide adenine dinucleotide co-immobilised on poly(pyrrole) functionalised controlled pore glass in water; acetonitrile T=20°C; pH=7.5; aq. potassium phosphate bufferElectrochemical regeneration of the co-factor (3 V/cm)Enzymatic reaction;
参考文献
Ngamsom; Hickey; Greenway; Littlechild; McCreedy; Watts; Wiles
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 10 p. 2419 - 2424
反应条件
ueber den sauren 3-Nitro-phthalsaeureester und dessen Brucinsalz;
参考文献
Matsumoto; Takeda; Iwata; Sakamoto; Ishida
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 6 p. 1191 - 1197
反应条件
1: With ozone in methanol Inert atmosphere; 2: With sodium tetrahydroborate Inert atmosphere;
参考文献
Hata, Takeshi; Bannai, Rie; Otsuki, Mamoru; Urabe, Hirokazu
Organic Letters, 2010 , vol. 12, # 5 p. 1012 - 1014
反应条件
1-N,N-dimethylaminonaphthalene; lithium 1) THF, -85 to -35 deg C, 2) THF, -20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Harada, Toshiro; Hayashiya, Toshio; Wada, Isao; Iwa-ake, Naoko; Oku, Akira
Journal of the American Chemical Society, 1987 , vol. 109, # 2 p. 527 - 532
反应条件
NADH-H+; horse liver alcohol dehydrogenase in phosphate buffer pH=7.5; 27 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Giacomini, Daria; Galletti, Paola; Quintavalla, Arianna; Gucciardo, Gabriele; Paradisi, Francesca
Chemical Communications, 2007 , # 39 p. 4038 - 4040
反应条件
1.1: catecholborane; [Rh(COD)2](1+)BF4(1-); (R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl / 1,2-dimethoxy-ethane / 0.5 h / -66 °C 1.2: 1,2-dimethoxy-ethane / -66 - 20 °C 2.1: n-BuLi / hexane; tetrahydrofuran / -78 - 20 °C 3.1: aq. NaOH; aq. H2O2 / methanol / 0 - 20 °C View Scheme
参考文献
Chen, Austin; Ren, Li; Crudden, Cathleen M.
Journal of Organic Chemistry, 1999 , vol. 64, # 26 p. 9704 - 9710
反应条件
1: n-BuLi / hexane; tetrahydrofuran / -78 - 20 °C 2: aq. NaOH; aq. H2O2 / methanol / 0 - 20 °C View Scheme
参考文献
Chen, Austin; Ren, Li; Crudden, Cathleen M.
Journal of Organic Chemistry, 1999 , vol. 64, # 26 p. 9704 - 9710
反应条件
ammonium formate; palladium on activated charcoal in ethanol 6 h; Heating; Yield givenYields of byproduct given. Title compound not separated from byproducts;
参考文献
Nandanan; Jayachandran; Phukan, Prodeep; Pais, Godwin C. G.; Sudalai
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998 , vol. 37, # 12 p. 1221 - 1227
