in further solvent(s)
addition of the grignard compound to the ester (solution in n-butyl ether) at -50°C, stirring at -40°C, 24 hours, warming to 20°C within 24 hours and stirring for 24 hours;;
in further solvent(s)
reaction in n-butyl ether at -20°C, 3 hours, stirring for 24 hours, warming to 20°C within 12 - 15 hours and heating to 50°C, 0.5 hours;;
in further solvent(s)
reaction in n-butyl ether at -20°C, 3 hours, stirring for 24 hours, warming to 20°C within 12 - 15 hours and heating to 50°C, 0.5 hours;;
