2-(7-氯-1H-吲哚-3-基)乙胺合成路线 （共 8 条）
反应条件
hydrogenchloride; ammonium hydroxide; hydrazine hydrate in methanol; ethanol; chloroform
参考文献
Eli Lilly and Company
Patent: US5500431 A1, 1996 ;
反应条件
1: diethyl ether / Heating
2: NH3 / dioxane
3: lithium aluminum hydride / tetrahydrofuran / Heating
View Scheme
参考文献
Wu, Tom Y. H.; Schulte, Peter G.
Organic Letters, 2002 , vol. 4, # 23 p. 4033 - 4035
反应条件
1: NH3 / dioxane
2: lithium aluminum hydride / tetrahydrofuran / Heating
View Scheme
参考文献
Wu, Tom Y. H.; Schulte, Peter G.
Organic Letters, 2002 , vol. 4, # 23 p. 4033 - 4035
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
Reflux;
参考文献
Nirogi, Ramakrishna V.S.; Kambhampati, Ramasastri; Kothmirkar, Prabhakar; Konda, Jagadishbabu; Bandyala, Thrinath Reddy; Gudla, Parandhama; Arepalli, Sobhanadri; Gangadasari, Narasimhareddy P.; Shinde, Anil K.; Deshpande, Amol D.; Dwarampudi, Adireddy; Chindhe, Anil K.; Dubey, Pramod Kumar
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 3 p. 443 - 450
反应条件
1: piperidine; acetic acid / benzene / Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / Reflux
View Scheme
参考文献
Nirogi, Ramakrishna V.S.; Kambhampati, Ramasastri; Kothmirkar, Prabhakar; Konda, Jagadishbabu; Bandyala, Thrinath Reddy; Gudla, Parandhama; Arepalli, Sobhanadri; Gangadasari, Narasimhareddy P.; Shinde, Anil K.; Deshpande, Amol D.; Dwarampudi, Adireddy; Chindhe, Anil K.; Dubey, Pramod Kumar
Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 , vol. 27, # 3 p. 443 - 450
反应条件
hydrogenchloride; potassium hydroxide; acetic acid
参考文献
Labor. franc. de Chimiotherapie
Patent: FR1180512 , 1958 ;
Full Text Show Details
Labor. franc. de Chimiotherapie
Patent: GB888413 , 1958 ;
参考文献
Labor. franc. de Chimiotherapie
Patent: US2920080 , 1958 ;
反应条件
tryptophan decarboxylase from Catharanthus roseus (Madagascar periwinkle); pyridoxal 5'-phosphate; 2-hydroxyethanethiol
T=30°C; pH=8.5; aq. phosphate bufferEnzymatic reaction; Kinetics;
参考文献
Runguphan, Weerawat; Qu, Xudong; O'Connor, Sarah E.
Nature, 2010 , vol. 468, # 7322 p. 461 - 467
