1,6:2,3-二酐-β-D-吡喃甘露糖合成路线 （共 17 条）
反应条件
1: 94 percent / pyridine
2: 80 percent / IRA 400 in OH(1-) form / methanol / 0.5 h
View Scheme
参考文献
Dolezalova, Jitka; Trnka, Tomas; Cerny, Miloslav
Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 9 p. 2415 - 2422
反应条件
1: 72 percent / MeONa / CH2Cl2 / 2 h / -15 °C
2: 63 percent / PdCl2, NaOAc / acetic acid; H2O / 4 h / 45 °C
View Scheme
参考文献
Thiem; Prahst; Lundt
1986 , vol. 1986, # 6 p. 1044 - 1056
反应条件
1.1: sodium methylate / methanol / 2 h
2.1: bis(tri-n-butyltin)oxide / acetonitrile / 16 h / |Molecular sieve
2.2: 3.25 h / 5 - 20 °C / |Inert atmosphere
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / -20 - 20 °C
View Scheme
参考文献
RELIABLE BIOPHARMACEUTICAL CORPORATION; PATEL, Payal Parth; MA, Chun; OHRR, Kevin K.; NADJI, Sourena
Patent: WO2013/115817 A1, 2013 ;
反应条件
1.1: bis(tri-n-butyltin)oxide / acetonitrile / 16 h / |Molecular sieve
1.2: 3.25 h / 5 - 20 °C / |Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / -20 - 20 °C
View Scheme
参考文献
RELIABLE BIOPHARMACEUTICAL CORPORATION; PATEL, Payal Parth; MA, Chun; OHRR, Kevin K.; NADJI, Sourena
Patent: WO2013/115817 A1, 2013 ;
反应条件
sodium methylate
0.75 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Tailler, Denis; Jaquinet, Jean-Claude; Noirot, Anne-Marie; Beau, Jean-Marie
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 23 p. 3163 - 3164
反应条件
T=520°C; P=20252 Torr; 1 h; High pressurePyrolysisFlow reactorInert atmosphere; PressureTemperature;
参考文献
Venkatakrishnan, Vinod Kumar; Degenstein, John C.; Smeltz, Andrew D.; Delgass, W. Nicholas; Agrawal, Rakesh; Ribeiro, Fabio H.
Green Chemistry, 2014 , vol. 16, # 2 p. 792 - 802
反应条件
1: 95 percent / NaH / dimethylformamide / 2 h / 20 °C
2: 80 percent / sodium azide / dimethylformamide; H2O / 120 °C
View Scheme
参考文献
Xue, Jie; Guo, Zhongwu
Tetrahedron Letters, 2001 , vol. 42, # 37 p. 6487 - 6489
