2-(4-氯苯甲酰基)环己酮合成路线 （共 4 条）
反应条件
1: cyclohexanone With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 0.75 h; Inert atmosphere;
2: 4-chloro-benzoyl chloride in tetrahydrofuran
T=20°C; 2 h; Inert atmosphere;
参考文献
Van Linden, Oscar P. J.; Wijtmans, Maikel; Roumen, Luc; Rotteveel, Lonneke; Leurs, Rob; De Esch, Iwan. J. P.
Journal of Organic Chemistry, 2012 , vol. 77, # 17 p. 7355 - 7363
反应条件
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in ethyl acetate
T=77°C;
参考文献
Bartlett, Samuel L.; Beaudry, Christopher M.
Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9852 - 9855
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; tri-n-octyl phosphine; isopropyl alcohol; sodium sulfite in anhydrous xylene
T=120°C; 15 h; Inert atmosphere;
参考文献
Obora, Yasushi; Nakamura, Kazuhiro; Hatanaka, Shintaro
Chemical Communications, 2012 , vol. 48, # 53 p. 6720 - 6722
反应条件
1: (COCl)2
2: LHMDS / tetrahydrofuran
View Scheme
参考文献
Sui, Zhihua; Guan, Jihua; Ferro, Michael P.; McCoy, Kathy; Wachter, Michael P.; Murray, William V.; Singer, Monica; Steber, Michele; Ritchie, Dave M.; Argentieri, Dennis C.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 6 p. 601 - 604
