(e)-p-甲氧基肉桂酸甲酯合成路线 （共 23 条）
反应条件
1: 3-(4-methoxy-phenyl)acrylic acid methyl ester With Oxonereg;; (R)-1,1'-binaphthyl-2,2'-dicarboxylic acid cyclic ester in 1,4-dioxane; water 26 h; 2: butan-1-ol With Serratia marcescens lipase on celit 25 h; Further stages.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 13 p. 4599 - 4601
反应条件
1.1: 66 percent / KBrO3; aq. H2SO4; aq. NaHSO3 / acetonitrile / 36 h 2.1: 94 percent / DMAP / CH2Cl2 / 20 °C 3.1: lipase AS Amano; aq. phosphate buffer / toluene / 48 h / 30 °C / pH 7.0 3.2: lipase AS Amano; aq. phosphate buffer / toluene / 33 h / 30 °C / pH 7.0 4.1: HCl / methanol / 24 h / 20 °C 5.1: DBU / CH2Cl2 / 0.58 h / 5 - 20 °C View Scheme
参考文献
Anand, Naveen; Kapoor, Munish; Koul, Surrinder; Taneja, Subhash C.; Sharma, Rattan L.; Qazi, Ghulam N.
Tetrahedron Asymmetry, 2004 , vol. 15, # 19 p. 3131 - 3138
反应条件
1: 99 percent / H2 / 10percent Pd/C / ethanol / 1 h / 25 °C / 2327.2 Torr 2: 94 percent / water, KOH / methanol / 2 h / 25 °C 3: 63 percent / polyphosphoric acid / 0.08 h / 120 °C View Scheme
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
1: DIBAL / 1 h / 0 °C 2: PDC / dimethylformamide / 1.5 h / 20 °C View Scheme
参考文献
Marshall; Whiting
Journal of the Chemical Society, 1956 , p. 4082,4087
反应条件
1: 99 percent / H2 / 10percent Pd/C / ethanol / 1 h / 25 °C / 2327.2 Torr 2: 94 percent / water, KOH / methanol / 2 h / 25 °C View Scheme
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
hydrogen; palladium on activated charcoal in ethanol T=25°C; P=2327.2 Torr; 1 h;
参考文献
THE UNIVERSITY OF HONG KONG
Patent: WO2007/41923 A1, 2007 ;
Location in patent: Page/Page column 19 ;
反应条件
tetraethylammonium p-toluenesulfonate in acetonitrile T=20°C; Electrolysis;
参考文献
Journal of Organic Chemistry, , vol. 67, # 24 p. 8305 - 8315
参考文献
Lewis; Ramage; Robinson
Journal of the Chemical Society, 1935 , p. 1412
Full Text Show Details
Ramage; Robinson
Journal of the Chemical Society, 1933 , p. 607,609
反应条件
1: DIBAL / 1 h / 0 °C 2: PDC / dimethylformamide / 1.5 h / 20 °C View Scheme
参考文献
Marshall; Whiting
Journal of the Chemical Society, 1956 , p. 4082,4087
反应条件
1: 1.) magnesium / 1.) ether, 2.) 25 deg C, 40 min 2: 60 percent / 1,4-dicyanonaphthalene (DCN) / acetonitrile; H2O / 2.5 h / Irradiation View Scheme
参考文献
Pandey, G.; Krishna, A.
Journal of Organic Chemistry, 1988 , vol. 53, # 10 p. 2364 - 2365
