11-甲氧基-11-氧代十一酸合成路线 （共 19 条）
反应条件
1: 36.3 percent / Pb(OAc)4, pyridine, Cu(OAc)2 / benzene / 3 h / Heating 2: 1) Br2, 2) aq.KOH / 1) CCl4, r.t., 2) 135-145 deg C, 4 h 3: 100 percent / conc.H2SO4 / 4 h / Heating 4: 83 percent / LAH / diethyl ether / 2 h / Ambient temperature 5: 98 percent / PPTS / CH2Cl2 / 4 h / Ambient temperature 6: 1) n-BuLi, 2) HMPT / 1) THF, hexane, 10 deg C, 2) <25 deg C, 0.5 h 7: 92 percent / PPTS / ethanol / 70 °C 8: 98 percent / H2, quinoline / 5percent Pd/BaSO4 / methanol View Scheme
参考文献
Ranganathan, S.; Maniktala, Vibha; Kumar, Raaj; Singh, G. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1197 - 1207
参考文献
Brichima S.p.A.
Patent: US4217290 A1, 1980 ;
反应条件
1: 36.3 percent / Pb(OAc)4, pyridine, Cu(OAc)2 / benzene / 3 h / Heating 2: 1) Br2, 2) aq.KOH / 1) CCl4, r.t., 2) 135-145 deg C, 4 h 3: 100 percent / conc.H2SO4 / 4 h / Heating 4: 83 percent / LAH / diethyl ether / 2 h / Ambient temperature View Scheme
参考文献
Ranganathan, S.; Maniktala, Vibha; Kumar, Raaj; Singh, G. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1197 - 1207
反应条件
1: 36.3 percent / Pb(OAc)4, pyridine, Cu(OAc)2 / benzene / 3 h / Heating 2: 1) Br2, 2) aq.KOH / 1) CCl4, r.t., 2) 135-145 deg C, 4 h 3: 100 percent / conc.H2SO4 / 4 h / Heating 4: 83 percent / LAH / diethyl ether / 2 h / Ambient temperature 5: 98 percent / PPTS / CH2Cl2 / 4 h / Ambient temperature View Scheme
参考文献
Ranganathan, S.; Maniktala, Vibha; Kumar, Raaj; Singh, G. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1197 - 1207
反应条件
1: 36.3 percent / Pb(OAc)4, pyridine, Cu(OAc)2 / benzene / 3 h / Heating 2: 1) Br2, 2) aq.KOH / 1) CCl4, r.t., 2) 135-145 deg C, 4 h 3: 100 percent / conc.H2SO4 / 4 h / Heating 4: 83 percent / LAH / diethyl ether / 2 h / Ambient temperature 5: 98 percent / PPTS / CH2Cl2 / 4 h / Ambient temperature 6: 1) n-BuLi, 2) HMPT / 1) THF, hexane, 10 deg C, 2) <25 deg C, 0.5 h View Scheme
参考文献
Ranganathan, S.; Maniktala, Vibha; Kumar, Raaj; Singh, G. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1197 - 1207
反应条件
pyridine; lead(IV) acetate; copper diacetate in benzene 3 h; Heating;
参考文献
Ranganathan, S.; Maniktala, Vibha; Kumar, Raaj; Singh, G. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1197 - 1207
反应条件
Electrolysis.anschliessendes Hydrolyse mit Hilfe von Alkalilauge;
参考文献
Serck-Hanssen
Chemistry and Industry (London, United Kingdom), 1958 , p. 1554
参考文献
Journal of the American Chemical Society, , vol. 51, p. 627
反应条件
in glycerol
T=180°C;
参考文献
Berdeaux, Olivier; Fontagne, Stephanie; Semon, Etienne; Velasco, Joaquin; Sebedio, Jean Louis; Dobarganes, Carmen
Chemistry and Physics of Lipids, 2012 , vol. 165, # 3 p. 338 - 347
反应条件
Sodium bromate; hydrogen bromide; tert-butyl alcohol in tetrachloromethane; water
2 h; Ambient temperature;
参考文献
Veeraiah, T.; Periasamy, M.
Synthetic Communications, 1989 , vol. 19, # 11-12 p. 2151 - 2158
