1-甲基-1,3-二氢-咪唑-2-酮合成路线 (共 6 条)
反应条件
hydrogenchloride in methanol; water
48 h; Ambient temperature;
参考文献
Wong, Ooi; Tsuzuki, Noriko; Richardson, Mark; Rytting, Howard; Konishi, Ryoji; Higuchi, Takeru
Heterocycles, 1987 , vol. 26, # 12 p. 3153 - 3158
反应条件
hydrogenchloride in methanol; water
72 h;
参考文献
Wong, Ooi; Tsuzuki, Noriko; Richardson, Mark; Rytting, Howard; Konishi, Ryoji; Higuchi, Takeru
Heterocycles, 1987 , vol. 26, # 12 p. 3153 - 3158
反应条件
trifluoroacetic acid in dichloromethane
0.5 h; Ambient temperature;
参考文献
Cortes; Liao; Watson; Kohn
Journal of Medicinal Chemistry, 1985 , vol. 28, # 5 p. 601 - 606
反应条件
hydrogenchloride
1.) EtOH, room temperature, 1 h; reflux, 4 h, 2.) H2O, overnight; Yield given. Multistep reaction;
参考文献
Coburn; Taylor; Wright
Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 12 p. 1322 - 1324
反应条件
hydrogenchloride; potassium cyanate
参考文献
Lawson
Journal of the Chemical Society, 1957 , p. 1443
反应条件
in water
Irradiation; Yields of byproduct given;
参考文献
Wenska; Skalski; Paszyc; Gdaniec
Canadian Journal of Chemistry, 1995 , vol. 73, # 12 p. 2178 - 2184