2-羟基-5-硝基苯甲腈合成路线 （共 26 条）
参考文献
Meyer,V.; Bone
Chemische Berichte, 1893 , vol. 26, p. 1254
参考文献
Brady; Bishop
Journal of the Chemical Society, 1925 , vol. 127, p. 1362
参考文献
Auwers; Walker
Chemische Berichte, 1898 , vol. 31, p. 3041
参考文献
Cousin; Volmar
Chem. Zentralbl., 1915 , vol. 86, # I p. 669
Full Text Show Details
Cousin; Volmar
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1914 , vol. 159, p. 330
Chem. Zentralbl., 1915 , vol. 86, # I p. 669
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate
P=2250.23 Torr; 1.5 h;
参考文献
BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2004/39764 A1, 2004 ;
Location in patent: Page/Page column 88-89 ;
WO 2004/039764 A1
反应条件
1: 88 percent / SnCl2 / ethanol / 70 °C
2: 50 percent / Na2CO3 / dioxane; H2O / 25 °C
View Scheme
参考文献
Zamri; Schalk; Pattus; Abdallah
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 6 p. 1147 - 1150
