2-氨基-4-氟苯酚合成路线

394-33-22-硝基-4-氟苯酚

399-97-32-氨基-4-氟苯酚

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1346982 A1, 2003 ;

399-97-32-氨基-4-氟苯酚

参考文献

SmithKline Beecham Corporation
Patent: US6262113 B1, 2001 ;
US 6262113 B1

109-60-4乙酸丙酯+

394-33-22-硝基-4-氟苯酚

399-97-32-氨基-4-氟苯酚

参考文献

Eastman Kodak Company
Patent: US6482985 B1, 2002 ;

371-41-54-氟苯酚

399-97-32-氨基-4-氟苯酚

参考文献

Ayrton, Stephen T.; Panova, Jekaterina; Michalik, Adam R.; Martin, William H.C.; Gallagher, Richard T.; Bowen, Richard D.
International Journal of Mass Spectrometry, 2013 , vol. 345-347, p. 120 - 131

399-97-32-氨基-4-氟苯酚+

598-21-0溴乙酰溴

398-63-0

参考文献

Geng, Bolin; Comita-Prevoir, Janelle; Eyermann, Charles J.; Reck, Folkert; Fisher, Stewart
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5432 - 5435

399-97-32-氨基-4-氟苯酚+

3674-13-32,3-二溴丙酸乙酯

220120-59-26-氟-3,4-二氢-2H-1,4-苯并噁嗪-2-羧酸乙酯

参考文献

Touzeau, Frederique; Arrault, Axelle; Guillaumet, Gerald; Scalbert, Elizabeth; Pfeiffer, Bruno; Rettori, Marie-Claire; Renard, Pierre; Merour, Jean-Yves
Journal of Medicinal Chemistry, 2003 , vol. 46, # 10 p. 1962 - 1979

399-97-32-氨基-4-氟苯酚+

78-39-7原乙酸三乙酯

701-16-65-氟-2-甲基苯并恶唑

参考文献

GE HEALTHCARE UK LIMITED
Patent: WO2008/40994 A2, 2008 ;
Location in patent: Page/Page column 25 ;

399-97-32-氨基-4-氟苯酚+

108-24-7乙酸酐

701-16-65-氟-2-甲基苯并恶唑

参考文献

Ayrton, Stephen T.; Panova, Jekaterina; Michalik, Adam R.; Martin, William H.C.; Gallagher, Richard T.; Bowen, Richard D.
International Journal of Mass Spectrometry, 2013 , vol. 345-347, p. 120 - 131

399-97-32-氨基-4-氟苯酚+

106-93-4二溴乙烷

105655-00-36-氟-3,4-二氢-2H-苯并[1,4]恶嗪

参考文献

Mizar, Pushpak; Myrboh, Bekington
Tetrahedron Letters, 2006 , vol. 47, # 44 p. 7823 - 7826

399-97-32-氨基-4-氟苯酚+

530-62-1N,N'-羰基二咪唑

13451-79-15-氟-2(3H)-苯并噁唑酮

参考文献

WO2005/18529 A2, ;

Page/Page column 62 ;
WO 2005/018529 A2