lithium hydroxide; tri-tert-butyl phosphine; palladium diacetate in ethylene glycol dimethyl ether; water T=25°C; Suzuki coupling reaction; 14 h;

1.1: Na2CO3 / H2O / 0.5 h / 20 °C 1.2: Na2CO3 / H2O / 2 h / 20 °C 2.1: 82 percent / LiOH*H2O; P(t-Bu)3 / Pd(OAc)2 / 1,2-dimethoxy-ethane; H2O / 14 h / 25 °C View Scheme

potassium tert-butylate in dimethyl sulfoxide 3 h; Inert atmosphereIrradiation;