反应条件
1: 90 percent / 1.) magnesium, iodine; 2.) CuBr / diethyl ether / 1.) 2.5 h, 34-36 degC; 2.) -30 degC, 5 min, allowed to warm to 0 degC over 1 h, 3 h, 0 degC
2: thionylchloride, pyridine / 7.5 h / Heating
3: 78 percent / sodium azide / dimethylsulfoxide / 8 h / 75 °C
4: 67 percent / hydrogen / 5percent Pd/CaCO3 / tetrahydrofuran / 18 h / 21 °C
View Scheme
参考文献
Goument, B.; Duhamel, L.; Mauge, R.
Bulletin de la Societe Chimique de France, 1993 , vol. 130, p. 450 - 458
