2-氯-5-甲基-4-硝基苯酚合成路线 （共 10 条）
反应条件
nitric acid; sodium nitrite
参考文献
Huegel, Helmut M.
Synthesis, 1983 , # 11 p. 935 - 936
反应条件
acetic acid
bei der Chlorierung;
参考文献
Raiford
Journal of the American Chemical Society, 1914 , vol. 36, p. 675
Full Text Show Details
Raiford
American Chemical Journal, 1911 , vol. 46, p. 447
Journal of the American Chemical Society, 1914 , vol. 36, p. 673
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Kehrmann
American Chemical Journal, vol. 303, p. 23
参考文献
Kenner; Tod; Witham
Journal of the Chemical Society, 1925 , vol. 127, p. 2348
参考文献
Kolbah; Blazevic; Hannoun; et al.
Helvetica Chimica Acta, 1977 , vol. 60, # 1 p. 265 - 283
参考文献
Raiford
Journal of the American Chemical Society, 1914 , vol. 36, p. 675
Full Text Show Details
Raiford
American Chemical Journal, 1911 , vol. 46, p. 447
Journal of the American Chemical Society, 1914 , vol. 36, p. 673
参考文献
Kenner; Tod; Witham
Journal of the Chemical Society, 1925 , vol. 127, p. 2348
反应条件
potassium carbonate in ethanol
参考文献
Batandier; Marsura; Luu-Duc
Farmaco, Edizione Scientifica, 1987 , vol. 42, # 3 p. 227 - 230
反应条件
1: aq. KOH
2: H2 / Raney-Ni / methanol
View Scheme
参考文献
Kolbah; Blazevic; Hannoun; et al.
Helvetica Chimica Acta, 1977 , vol. 60, # 1 p. 265 - 283
反应条件
1: 80 percent / K2CO3 / ethanol
2: 80 percent / dimethylformamide / 48 h / Heating
3: 54 percent / powdered iron / ethanol; acetic acid / 3 h / Heating
View Scheme
参考文献
Batandier; Marsura; Luu-Duc
Farmaco, Edizione Scientifica, 1987 , vol. 42, # 3 p. 227 - 230
反应条件
1: 75 percent
2: dimethylformamide / 6 h / 130 °C
3: H2 / Raney-Ni / 2896.03 Torr
4: diethyl ether / 0.5 h / 0 °C
5: NH3 / toluene
6: 1.) (CH3)2S*BH3, 2.) aq. HCl / 1.) THF, reflux, 30 min, 2.) 100 deg C, 20 min
7: pyridine / ethyl acetate / Ambient temperature
View Scheme
参考文献
Huegel, Helmut M.
Synthesis, 1983 , # 11 p. 935 - 936
