(2-氨基-4,5,6,7-四氢-1-苯并噻吩-3-基)(4-氯苯基)甲酮合成路线 （共 5 条）
反应条件
hydrogen; triethylamine; palladium on activated charcoal in 1,4-dioxane; methanol
P=2585.74 Torr;
参考文献
Baraldi, Pier Giovanni; Pavani, Maria Giovanna; Leung, Edward; Moorman, Allan R.; Varani, Katia; Vincenzi, Fabrizio; Borea, Pier Andrea; Romagnoli, Romeo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1402 - 1404
反应条件
sulfur; diethylamine in ethanol
T=50°C; Condensation; 2 h;
参考文献
Van Der Klein, Pieter A. M.; Kourounakis, Angeliki P.; IJzerman, Ad P.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 18 p. 3629 - 3635
反应条件
1: S; morpholine / ethanol
2: 80 percent / Et3N; H2 / Pd/C / methanol; dioxane / 2585.74 Torr
View Scheme
参考文献
Baraldi, Pier Giovanni; Pavani, Maria Giovanna; Leung, Edward; Moorman, Allan R.; Varani, Katia; Vincenzi, Fabrizio; Borea, Pier Andrea; Romagnoli, Romeo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1402 - 1404
反应条件
1: NaH
2: S; morpholine / ethanol
3: 80 percent / Et3N; H2 / Pd/C / methanol; dioxane / 2585.74 Torr
View Scheme
参考文献
Baraldi, Pier Giovanni; Pavani, Maria Giovanna; Leung, Edward; Moorman, Allan R.; Varani, Katia; Vincenzi, Fabrizio; Borea, Pier Andrea; Romagnoli, Romeo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1402 - 1404
反应条件
1: S; morpholine / ethanol
2: 80 percent / Et3N; H2 / Pd/C / methanol; dioxane / 2585.74 Torr
View Scheme
参考文献
Baraldi, Pier Giovanni; Pavani, Maria Giovanna; Leung, Edward; Moorman, Allan R.; Varani, Katia; Vincenzi, Fabrizio; Borea, Pier Andrea; Romagnoli, Romeo
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 5 p. 1402 - 1404
