2-(苯基甲氧基)-苯乙酸甲酯合成路线 （共 14 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Imperial Chemical Industries PLC
Patent: US4870075 A1, 1989 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Imperial Chemical Industries PLC
Patent: US5057146 A1, 1991 ;
反应条件
potassium carbonate in N-methyl-acetamide
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US6207686 B1, 2001 ;
反应条件
sulfuric acid; iso-propylmagnesium bromide; sodium hydrogencarbonate
Yield given. Multistep reaction;
参考文献
Schultz,A.G.; Napier,J.J.; Sundararam,P.
Journal of the American Chemical Society, 1984 , vol. 106, p. 3590
反应条件
sulfuric acid
2 h; Heating;
参考文献
Lee, Jeewoo; Lee, Ju-Hyun; Kim, Su Yeon; Perry, Nicholas A.; Lewin, Nancy E.; Ayres, Jolene A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2022 - 2031
反应条件
hydrogenchloride
Heating;
参考文献
Wang, Zhongwen; Li, Zhengming; Liu, Tianlin; Ren, Jun
Synthetic Communications, 1999 , vol. 29, # 13 p. 2361 - 2364
反应条件
1: 94 percent / potassium carbonate / acetone / 4 h / Heating
2: 92 percent / thionyl chloride / CH2Cl2 / 3 h / 0 °C
3: 96 percent / dimethylformamide / 2 h / 100 °C
4: 97 percent / NaOH / H2O / Heating
5: 90 percent / H2SO4 / 2 h / Heating
View Scheme
参考文献
Lee, Jeewoo; Lee, Ju-Hyun; Kim, Su Yeon; Perry, Nicholas A.; Lewin, Nancy E.; Ayres, Jolene A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2022 - 2031
反应条件
1: 92 percent / thionyl chloride / CH2Cl2 / 3 h / 0 °C
2: 96 percent / dimethylformamide / 2 h / 100 °C
3: 97 percent / NaOH / H2O / Heating
4: 90 percent / H2SO4 / 2 h / Heating
View Scheme
参考文献
Lee, Jeewoo; Lee, Ju-Hyun; Kim, Su Yeon; Perry, Nicholas A.; Lewin, Nancy E.; Ayres, Jolene A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2022 - 2031
反应条件
1: 97 percent / NaOH / H2O / Heating
2: 90 percent / H2SO4 / 2 h / Heating
View Scheme
参考文献
Lee, Jeewoo; Lee, Ju-Hyun; Kim, Su Yeon; Perry, Nicholas A.; Lewin, Nancy E.; Ayres, Jolene A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2022 - 2031
反应条件
1: 94 percent / potassium carbonate / acetone / 4 h / Heating
2: 92 percent / thionyl chloride / CH2Cl2 / 3 h / 0 °C
3: 96 percent / dimethylformamide / 2 h / 100 °C
4: 97 percent / NaOH / H2O / Heating
5: 90 percent / H2SO4 / 2 h / Heating
View Scheme
参考文献
Lee, Jeewoo; Lee, Ju-Hyun; Kim, Su Yeon; Perry, Nicholas A.; Lewin, Nancy E.; Ayres, Jolene A.; Blumberg, Peter M.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 6 p. 2022 - 2031
