2-亚甲基环己烷-1-醇合成路线 （共 70 条）
反应条件
1: m-CPBA / CH2Cl2
2: 90 percent / AlEt3 / tetrahydrofuran / 40 °C
View Scheme
参考文献
Wang, Fei; Wang, Shao Hua; Tu, Yong Qiang; Ren, Shi Kuo
Tetrahedron Asymmetry, 2003 , vol. 14, # 15 p. 2189 - 2193
反应条件
1: 97.5 percent / TsOH / benzene / Heating
2: sodium periodate
3: 72 percent Spectr. / PhSNa
View Scheme
参考文献
Hannaby, Malcolm; Warren, Stuart
Tetrahedron Letters, 1985 , vol. 26, # 26 p. 3133 - 3136
反应条件
1: 1.16 g / diethyl ether / 1 h / Ambient temperature
2: 506 mg / MCPBA / CHCl3 / 5 h / 0 °C
3: 38 percent / NaH / tetrahydrofuran / 15 h / Heating
View Scheme
参考文献
Masamune, Tadashi; Sato, Shingo; Abiko, Atsushi; Ono, Mitsunori; Murai, Akio
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 10 p. 2895 - 2904
反应条件
1: 506 mg / MCPBA / CHCl3 / 5 h / 0 °C
2: 38 percent / NaH / tetrahydrofuran / 15 h / Heating
View Scheme
参考文献
Masamune, Tadashi; Sato, Shingo; Abiko, Atsushi; Ono, Mitsunori; Murai, Akio
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 10 p. 2895 - 2904
反应条件
triphenylphosphine in chloroform-d1
also with LiAlH4 in ether;
参考文献
Courtneidge, John L.; Bush, Melanie; Loh, Lay-See
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 12 p. 1539 - 1548
反应条件
1: H2 / Raney-Ni / 54720 Torr
2: Py
3: aq. KOH / 150 - 160 °C
View Scheme
参考文献
Kovacs,E. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1962 , p. 116 - 122
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1962 , # 1 p. 130 - 138
反应条件
lithium aluminium tetrahydride
参考文献
Konzelman,L.M.; Conley,R.T.
Journal of Organic Chemistry, 1968 , vol. 33, p. 3828 - 3838
反应条件
potassium tert-butylate; dimethyl sulfoxide
T=100°C; 4 h; Yield given. Yields of byproduct given;
参考文献
Mikhaleva, A. I.; Petrova, O. V.; Bzhezovskii, V. M.; Kalinina, N. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1987 , vol. 36, # 7 p. 1555 - 1556
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1987 , # 7 p. 1677 - 1678
反应条件
potassium hydroxide
T=110°C; 1 h;
参考文献
Trofimov, B. A.; Mikhaleva, A. I.; Petrova, O. V.; Sigalov, M. B.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 10 p. 1889 - 1894
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 10 p. 2095 - 2101
反应条件
in pentane
Ambient temperature;
参考文献
Schakel, Marius; Luitjes, Hendrikus; Dewever, Frank L. M.; Scheele, Jan; Klumpp, Gerhard W.
Journal of the Chemical Society, Chemical Communications, 1995 , # 5 p. 513 - 514
