N-(1-环己烯)甲酰胺合成路线 （共 10 条）
反应条件
potassium tert-butylate in tetrahydrofuran 6 h; Heating;
参考文献
Keating; Armstrong
Journal of the American Chemical Society, 1996 , vol. 118, # 11 p. 2574 - 2583
反应条件
1H-imidazole; titanium acetate; acetic acid formic acid anhydrate in N,N-dimethyl-formamide T=25°C; 4 h;
参考文献
Barton, H. R. Derek; Bowles, Timothy; Husinec, Suren; Forbes, Judith E.; Llobera, Antonia; et al.
Tetrahedron Letters, 1988 , vol. 29, # 27 p. 3343 - 3346
反应条件
sulfuric acid in toluene Condensation; 12 h; HeatingDean-Stark-conditions;
参考文献
Maison, Wolfgang; Schlemminger, Imre; Westerhoff, Ole; Martens, Juergen
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 6 p. 1343 - 1360
反应条件
1: 53 percent / Ac2O / 12 h / 23 °C 2: 74 percent / t-BuOK / tetrahydrofuran / 6 h / Heating View Scheme
参考文献
Kurtz,P.; Disselnkoetter,H.
Justus Liebigs Annalen der Chemie, 1972 , vol. 764, p. 69 - 93
反应条件
triphenylphosphine; methyloxirane in dichloromethane 18 h; Ambient temperature;
参考文献
Baldwin, J.E.; Aldous, D.J.; ONeil, I.A.
Tetrahedron Letters, 1990 , vol. 31, # 14 p. 2051 - 2054
反应条件
1: 61 percent / aq. NH4Cl / diethyl ether / 23 °C 2: 53 percent / Ac2O / 12 h / 23 °C 3: 74 percent / t-BuOK / tetrahydrofuran / 6 h / Heating View Scheme
参考文献
Keating; Armstrong
Journal of the American Chemical Society, 1996 , vol. 118, # 11 p. 2574 - 2583
反应条件
1: liq. NH3 / methanol 2: HCO2H 3: 590 °C / 14 Torr View Scheme
参考文献
Kurtz,P.; Disselnkoetter,H.
Justus Liebigs Annalen der Chemie, 1972 , vol. 764, p. 69 - 93
反应条件
pyridine; 2,4,6-trichloro-1,3,5-triazine in dichloromethane T=100°C; 0.166667 h; microwave irradiation;
参考文献
Porcheddu, Andrea; Giacomelli, Giampaolo; Salaris, Margherita
Journal of Organic Chemistry, 2005 , vol. 70, # 6 p. 2361 - 2363
反应条件
trifluoromethylsulfonic anhydride; i-PrNEt; 3,3-dimethyldioxirane 1.) CH2Cl2, -40 deg C; 2.) -78 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Baldwin, J. E.; ONeil, I. A.
Tetrahedron Letters, 1990 , vol. 31, # 14 p. 2047 - 2050
反应条件
1: 60 percent / diazabicyclo<2.2.2>octane, triethylenediamine, triphosgene / CH2Cl2 / 0.5 h / 0 °C 2: methanol / 12 h / Ambient temperature View Scheme
参考文献
Keating; Armstrong
Journal of the American Chemical Society, 1996 , vol. 118, # 11 p. 2574 - 2583
