Γ-氯-4-甲氧基苯丁酮合成路线 （共 16 条）
反应条件
sodium azide; triethyl phosphite in dimethyl sulfoxide
intramolecular aza-Wittig reaction; 0.333333 h; microwave irradiation;
参考文献
Singh, Pradeep N.D.; Klima, Rodney F.; Muthukrishnan, Sivaramakrishnan; Murthy, Rajesh S.; Sankaranarayanan, Jagadis; Stahlecker, Heidi M.; Patel, Bhavika; Gudmundsdottir, Anna D.
Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4213 - 4217
反应条件
potassium carbonate; sodium iodide in N,N-dimethyl-formamide
T=90°C;
参考文献
Ngu, Khehyong; Weinstein, David S.; Liu, Wen; Langevine, Charles; Combs, Donald W.; Zhuang, Shaobin; Chen, Xing; Madsen, Cort S.; Harper, Timothy W.; Ahmad, Saleem; Robl, Jeffrey A.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4141 - 4145
反应条件
toluene-4-sulfonic acid in toluene
Inert atmosphereReflux;
参考文献
Tewes, Bastian; Frehland, Bastian; Schepmann, Dirk; Schmidtke, Kai-Uwe; Winckler, Thomas; Wuensch, Bernhard
ChemMedChem, 2010 , vol. 5, # 5 p. 687 - 695
反应条件
triethylamine in acetonitrile
7 h; Heating;
参考文献
Shen, Yanhong; Sheng, Rong; Zhang, Jing; He, Qiaojun; Yang, Bo; Hu, Yongzhou
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 16 p. 7646 - 7653
反应条件
triethylamine in acetonitrile
7 h; Heating;
参考文献
Shen, Yanhong; Sheng, Rong; Zhang, Jing; He, Qiaojun; Yang, Bo; Hu, Yongzhou
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 16 p. 7646 - 7653
反应条件
1: 75 percent / NaI / acetone / Heating
2: 72 percent / Ni(acac)2; acetophenone / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 12 h / -35 °C
View Scheme
参考文献
Giovannini; Strudemann; Devasagayaraj; Dussin; Knochel
Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3544 - 3553
