5,5-二甲基-1,3,2-二氧磷杂环己烷-2-酮合成路线 （共 23 条）
反应条件
tetrachloromethane; triethylamine in diethyl ether
参考文献
Nifant'ev,E.E.; Matveeva,L.M.
J. Gen. Chem. USSR (Engl. Transl.), 1969 , vol. 39, p. 1555 - 1558,1525 - 1527
反应条件
N-ethyl-N-hydroxyethylamine T=70°C; 3 h;
参考文献
Grachev, M. K.; Nifant'ev, E. E.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 8.1 p. 1729 - 1733,1538 - 1541
参考文献
Nifant'ev,E.E.; Matveeva,L.M.
J. Gen. Chem. USSR (Engl. Transl.), 1969 , vol. 39, p. 1555 - 1558,1525 - 1527
参考文献
Grachev, M. K.; Nifant'ev, E. E.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 8.1 p. 1729 - 1733,1538 - 1541
反应条件
unter vermindertem Druck auf 130grad;
参考文献
Oswald
Canadian Journal of Chemistry, 1959 , vol. 37, p. 1498,1499,1503
反应条件
triethylamine in toluene
参考文献
Praveen Kumar, K; Muthiah, C; Kumaraswamy, Sudha; Kumara Swamy
Tetrahedron Letters, 2001 , vol. 42, # 18 p. 3219 - 3221
反应条件
1H-imidazole in acetonitrile 4 h; Heating;
参考文献
Morita, Iwao; Chokai, Shoichi; Tsuda, Masami; Kise, Masahiro; Sugiyama, Makoto
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 3 p. 1135 - 1138
反应条件
1: 5,5-dimethyl-1,3,2λ5-dioxaphosphinan-2-one With sodium hydride in tetrahydrofuran
T=20°C; 1 h;
2: methyl iodide in tetrahydrofuran
T=20°C; 12 h;
参考文献
Lee, Sunggi; Kim, Sunggak
Organic Letters, 2008 , vol. 10, # 19 p. 4255 - 4258
反应条件
iodosylbenzene in tetrahydrofuran
12 h; Heating;
参考文献
Makowiec, Slawomir; Rachon, Janusz
Phosphorus, Sulfur and Silicon and Related Elements, 2002 , vol. 177, # 4 p. 941 - 955
反应条件
1: toluene / 20 °C
2: sodium tungstate; dihydrogen peroxide / water / 48 h / 0 °C
View Scheme
参考文献
Gosset, Gaelle; Clement, Jean-Louis; Culcasi, Marcel; Rockenbauer, Antal; Pietri, Sylvia
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 7 p. 2218 - 2230
