(1-(4-甲基哌嗪-1-基)环己基)甲胺合成路线 (共 3 条)
反应条件
1: zinc(II) iodide / methanol; diethyl ether / 8 h / 80 °C
2: lithium aluminium tetrahydride / diethyl ether / Reflux
View Scheme
参考文献
McClure, Kelly J.; Maher, Michael; Wu, Nancy; Chaplan, Sandra R.; Eckert III, William A.; Lee, Dong H.; Wickenden, Alan D.; Hermann, Michelle; Allison, Brett; Hawryluk, Natalie; Breitenbucher, J. Guy; Grice, Cheryl A.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5197 - 5201
反应条件
1: zinc(II) iodide / methanol; diethyl ether / 8 h / 80 °C
2: lithium aluminium tetrahydride / diethyl ether / Reflux
View Scheme
参考文献
McClure, Kelly J.; Maher, Michael; Wu, Nancy; Chaplan, Sandra R.; Eckert III, William A.; Lee, Dong H.; Wickenden, Alan D.; Hermann, Michelle; Allison, Brett; Hawryluk, Natalie; Breitenbucher, J. Guy; Grice, Cheryl A.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5197 - 5201
反应条件
lithium aluminium tetrahydride in diethyl ether
Reflux;
参考文献
McClure, Kelly J.; Maher, Michael; Wu, Nancy; Chaplan, Sandra R.; Eckert III, William A.; Lee, Dong H.; Wickenden, Alan D.; Hermann, Michelle; Allison, Brett; Hawryluk, Natalie; Breitenbucher, J. Guy; Grice, Cheryl A.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5197 - 5201