(R)-(-)-1,2-二苯基乙醇合成路线 （共 25 条）
反应条件
1: With [Rh[(R)-BINAP](COD)]BF4; benzo[1,3,2]dioxaborole in tetrahydrofuran
T=25°C; 2 h;
2: With sodium hydroxide; dihydrogen peroxide in ethanol
Further byproducts given;
参考文献
Ramirez, Jesus; Segarra, Anna M.; Fernandez, Elena
Tetrahedron Asymmetry, 2005 , vol. 16, # 7 p. 1289 - 1294
反应条件
Sc(OTf)3-chiral bipyridine complex in dichloromethane
8 h; Title compound not separated from byproducts.;
参考文献
Tschoep, Andreas; Nandakumar, Mecheril Valsan; Pavlyuk, Oksana; Schneider, Christoph
Tetrahedron Letters, 2008 , vol. 49, # 6 p. 1030 - 1033
反应条件
tetraproline chiral stationary phase packed on HPLC column in hexane; isopropyl alcohol
Resolution of racemate;
参考文献
Dai, Zhi; Ye, Guozhong; Pittman Jr., Charles U.; Li, Tingyu
Chirality, 2012 , vol. 24, # 4 p. 329 - 338
反应条件
sodium hydroxide; dihydrogen peroxide; (-)-Monoisopinocampheylborane
1.) a.) THF, -25 deg C, 24 h, b.) 0 deg C, 48 deg C, 2.) 55 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brown, Herbert C.; Jadhav, Prabhakar K.; Mandal, Arun K.
Journal of Organic Chemistry, 1982 , vol. 47, # 26 p. 5074 - 5083
反应条件
sodium tetrahydroborate; zirconium tetrachloride; L-proline in tetrahydrofuran
3 h; Ambient temperatureregioselective cleavage;
参考文献
Santosh Laxmi; Iyengar
Synthetic Communications, 1997 , vol. 27, # 10 p. 1731 - 1736
