2-羟基-5-甲氧基苄醇合成路线 （共 22 条）
反应条件
lithium aluminium tetrahydride
参考文献
Meier, Chris; De Clercq, Eric; Balzarini, Jan
European Journal of Organic Chemistry, 1998 , # 5 p. 837 - 846
反应条件
sodium tetrahydroborate in ethanol
T=20°C; 1 h;
参考文献
Ono, Masahiro; Kawashima, Hidekazu; Nonaka, Akemi; Kawai, Tomoki; Haratake, Mamoru; Mori, Hiroshi; Kung, Mei-Ping; Kung, Hank F.; Saji, Hideo; Nakayama, Morio
Journal of Medicinal Chemistry, 2006 , vol. 49, # 9 p. 2725 - 2730
反应条件
sodium metaborate tetrahydrate in water
T=40°C; 12 h; Green chemistry; regioselective reaction;
参考文献
Li, Hui-Jing; Wu, Ying-Ying; Wu, Qin-Xi; Wang, Rui; Dai, Chun-Yang; Shen, Zhi-Lun; Xie, Cheng-Long; Wu, Yan-Chao
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 19 p. 3100 - 3107
反应条件
sodium hydrogencarbonate in acetonitrile
T=80°C;
参考文献
Weinert, Emily E.; Dondi, Ruggero; Colloredo-Melz, Stefano; Frankenfield, Kristen N.; Mitchell, Charles H.; Freccero, Mauro; Rokita, Steven E.
Journal of the American Chemical Society, 2006 , vol. 128, # 36 p. 11940 - 11947
反应条件
in ethylene glycol dimethyl ether; xylene
T=135°C; 12 h;
参考文献
Casiraghi, Giovanni; Casnati, Giuseppe; Puglia, Giuseppe; Sartori, Giovanni
Synthesis, 1980 , # 2 p. 124 - 125
反应条件
dihydrogen peroxide in dimethyl sulfoxide
T=20°C; 336 h;
参考文献
Cao, Sheng; Christiansen, Robin; Peng, Xiaohua
Chemistry - A European Journal, 2013 , vol. 19, # 27 p. 9050 - 9058
反应条件
water
T=25°C; pH=7; Kinetics;
参考文献
Weinert, Emily E.; Dondi, Ruggero; Colloredo-Melz, Stefano; Frankenfield, Kristen N.; Mitchell, Charles H.; Freccero, Mauro; Rokita, Steven E.
Journal of the American Chemical Society, 2006 , vol. 128, # 36 p. 11940 - 11947
反应条件
RPMI culture medium
T=37°C; pH 4.6, 6.9, 7.3, 8.9; half-lives; influence of 10percent heat-inactivated fetal calf serum;
参考文献
Meier, Chris; De Clercq, Eric; Balzarini, Jan
Nucleosides and Nucleotides, 1997 , vol. 16, # 5-6 p. 793 - 796
反应条件
1: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 48 h / 85 °C / |Inert atmosphere
2: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / acetonitrile / 2 h / 90 °C / |Inert atmosphere
3: dihydrogen peroxide / dimethyl sulfoxide / 336 h / 20 °C
View Scheme
参考文献
Cao, Sheng; Christiansen, Robin; Peng, Xiaohua
Chemistry - A European Journal, 2013 , vol. 19, # 27 p. 9050 - 9058
反应条件
1: alkaline solution
2: lime milk
View Scheme
参考文献
Helfer
Helvetica Chimica Acta, 1924 , vol. 7, p. 955
