1: 69 percent / 50percent NaOH, tetrabutylammonium bromide / tetrahydrofuran / 18 h / Ambient temperature
2: 70 percent / Dibal-H / toluene / 0.25 h / 100 °C
View Scheme
参考文献
Janssen, Cornelus G. M.; Hendriks, Adrianus H. M.; Godefroi, Erik F.
Recueil: Journal of the Royal Netherlands Chemical Society, 1984 , vol. 103, # 7-8 p. 220 - 224
1: 69 percent / 50percent NaOH, tetrabutylammonium bromide / tetrahydrofuran / 18 h / Ambient temperature
2: 70 percent / Dibal-H / toluene / 0.25 h / 100 °C
View Scheme
参考文献
Janssen, Cornelus G. M.; Hendriks, Adrianus H. M.; Godefroi, Erik F.
Recueil: Journal of the Royal Netherlands Chemical Society, 1984 , vol. 103, # 7-8 p. 220 - 224
1.1: potassium tert-butylate / toluene; tetrahydrofuran / 4 h / |Inert atmosphere
1.2: 3 h / -78 - 20 °C / |Inert atmosphere
2.1: palladium on activated charcoal; hydrogen / ethyl acetate / 3 h / |Inert atmosphere
View Scheme
参考文献
Bess, Elizabeth N.; Deluca, Ryan J.; Tindall, Daniel J.; Oderinde, Martins S.; Roizen, Jennifer L.; Du Bois; Sigman, Matthew S.
Journal of the American Chemical Society, 2014 , vol. 136, # 15 p. 5783 - 5789
