2-(溴甲基)丙烯酸甲酯合成路线 （共 27 条）
反应条件
1: With bis(η5-cyclopentadienyl)titanium dichloride in tetrahydrofuran
T=20°C; 5 h;
2: With sulfuric acid in tetrahydrofuran
10 h;
参考文献
Paira, Moumita; Banerjee, Biplab; Jana, Samaresh; Mandal, Samir Kumar; Roy, Subhas Chandra
Tetrahedron Letters, 2007 , vol. 48, # 18 p. 3205 - 3207
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1405852 A1, 2004 ;
Location in patent: Page 134 ;
EP 1405852 A1
反应条件
sodium methylate in methanol
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: US2005/20645 A1, 2005 ;
反应条件
1: diethyl ether
2: NaH / tetrahydrofuran
View Scheme
参考文献
Gompper,R.; Ulrich,W.-R.
Angewandte Chemie, 1976 , vol. 88, p. 300 - 301
反应条件
1: 2-(bromomethyl)propenoic acid methyl ester; phosphonic acid diethyl ester With CaO
T=20°C; 18 h;
2: ethanol chemoselective reaction;
参考文献
Martinez-Castro, Elisa; Lopez, Oscar; Maya, Ines; Fernandez-Bolanos, Jose G.; Petrini, Marino
Green Chemistry, 2010 , vol. 12, # 7 p. 1171 - 1174
反应条件
sodium hydride in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Padwa, Albert; Murphree, S. Shaun; Ni, Zhijie; Watterson, Scott H.
Journal of Organic Chemistry, 1996 , vol. 61, # 11 p. 3829 - 3838
反应条件
indium in tetrahydrofuran; water
T=25°C; Barbier Coupling Reaction; 12 h; Inert atmosphere;
参考文献
Nicponski, Daniel R.
Tetrahedron Letters, 2014 , vol. 55, # 13 p. 2075 - 2077
