2-(2-羟基乙基)苯甲酸合成路线 （共 7 条）
参考文献
Wegler; Frank
Chemische Berichte, 1937 , vol. 70, p. 1279,1285
反应条件
1: diazomethyl-trimethyl-silane / methanol; tetrahydrofuran / 0 °C / |Inert atmosphere 2: pyridine; p-toluenesulfonyl chloride / chloroform / 0 - 20 °C / |Inert atmosphere 3: lithium bromide / acetone / 5 h / |Inert atmosphere; |Reflux View Scheme
参考文献
ALLERGAN, INC.; YUAN, HAIQING; BEARD, RICHARD L.; LIU, XIAOXIA; DONELLO, JOHN E.; VISWANATH, VEENA; GARST, MICHAEL E.
Patent: US2013/231338 A1, 2013 ;
参考文献
Watanabe, Yutaka; Ishimaru, Masanori; Ozaki, Shoichiro
Chemistry Letters, 1994 , # 11 p. 2163 - 2166
反应条件
water; iron(III) chloride in acetone
T=0°C; 8 h; Irradiation;
参考文献
Barbier, Michel
Helvetica Chimica Acta, 1984 , vol. 67, # 3 p. 866 - 869
反应条件
1: selenium(IV) oxide / anhydrous xylene / 44 h / 140 °C
2: potassium hydroxide / diethyl ether / 12 h / 20 °C
View Scheme
参考文献
ALLERGAN, INC.; YUAN, HAIQING; BEARD, RICHARD L.; LIU, XIAOXIA; DONELLO, JOHN E.; VISWANATH, VEENA; GARST, MICHAEL E.
Patent: US2013/231338 A1, 2013 ;
反应条件
1: dinitrogen tetraoxide; acetic acid
2: aq. NaOH solution
View Scheme
参考文献
Wegler; Frank
Chemische Berichte, 1937 , vol. 70, p. 1279,1285
参考文献
Wegler; Frank
Chemische Berichte, 1937 , vol. 70, p. 1279,1285
