2-(1-苯基乙基)苯酚合成路线 （共 31 条）
反应条件
1: With antimony trichloride in acetonitrile
T=65°C; 0.416667 h; Microwave irradiation;
2: With boron tribromide in dichloromethane
T=-20 - 0°C;
参考文献
Shukla, Prashant; Choudhary, Manoj K.; Nayak, Sandip K.
Synlett, 2011 , # 11 p. 1585 - 1591
反应条件
aluminium phenoxide
T=110°C; 3 h;
参考文献
Kochnev; Oleynik; Ivanchev; Tolstikov
Russian Chemical Bulletin, 2007 , vol. 56, # 6 p. 1125 - 1129
反应条件
sulfuric acid; acetic acid
inactive α-phenyl-α-<4-oxy-phenyl>-ethane;
参考文献
Stoermer; Kippe
Chemische Berichte, 1903 , vol. 36, p. 4002
反应条件
cyclopentene in toluene
T=100°C; Inert atmosphere; regioselective reaction;
参考文献
Lee, Dong-Hwan; Kwon, Ki-Hyeok; Yi, Chae S.
Journal of the American Chemical Society, 2012 , vol. 134, # 17 p. 7325 - 7328
反应条件
trimethylsilyl iodide in dichloromethane
T=20°C; 24 h;
参考文献
Sugiyama, Shigeo; Morishita, Kenji; Ishii, Keitaro
Heterocycles, 2001 , vol. 55, # 2 p. 353 - 364
反应条件
cyclopentene in toluene
T=100°C; 8 h; Inert atmosphere; regioselective reaction;
参考文献
Lee, Dong-Hwan; Kwon, Ki-Hyeok; Yi, Chae S.
Journal of the American Chemical Society, 2012 , vol. 134, # 17 p. 7325 - 7328
反应条件
1: Bromure de phenyl magnesium; carbonic acid tert-butyl ester 2-formyl-phenyl ester in diethyl ether
T=-78°C; Grignard reaction;
2: methyl-magnesium chloride in diethyl ether
T=20°C; Grignard reaction;
参考文献
Jones; Van De Water; Lindsey; Hoarau; Ung; Pettus
Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3435 - 3441
反应条件
1: 2-(phenylmethyl)phenol With sec.-butyllithium; (-)-sparteine
T=-78 - 0°C;
2: methyl iodide T=-78°C; Further stages.;
参考文献
Wilkinson, James A.; Rossington, Stephen B.; Leonard, John; Hussein, Nigel
Tetrahedron Letters, 2004 , vol. 45, # 6 p. 1191 - 1193
参考文献
Wheatley; Cheney; Binkley
Journal of the American Chemical Society, 1949 , vol. 71, p. 64
反应条件
1.1: 87 percent / NaH / tetrahydrofuran / 4 h / 20 °C
2.1: diethyl ether / -78 °C
2.2: 71 percent / diethyl ether / 20 °C
View Scheme
参考文献
Jones; Van De Water; Lindsey; Hoarau; Ung; Pettus
Journal of Organic Chemistry, 2001 , vol. 66, # 10 p. 3435 - 3441
