1,2,3,4-四氢吖啶-9-羧酸酰胺合成路线 （共 7 条）
反应条件
methanol; bromine; sodium methylate Erwaermen des Reaktionsprodukts mit wss. H2SO4;
参考文献
Ettel; Neumann
Collection of Czechoslovak Chemical Communications, 1958 , vol. 23, p. 1319
参考文献
Bayer and Co.
Patent: DE290703 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 724
反应条件
trichlorophosphate Heating;
参考文献
Del Giudice, Maria Rosaria; Borioni, Anna; Mustazza, Carlo; Gatta, Franco
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 6 p. 1661 - 1667
反应条件
1: 90 percent / 30percent aq. H2O2 / acetic acid / 5 h / 80 °C 2: 72 percent / 1 h / 90 °C 3: 76 percent / Br2, MeOH / 0.33 h / Heating 4: 64 percent / aq. KOH / methanol / 4 h / Heating View Scheme
参考文献
Del Giudice, Maria Rosaria; Borioni, Anna; Mustazza, Carlo; Gatta, Franco
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 6 p. 1661 - 1667
反应条件
1: bromine; sodium methylate; methanol / Erwaermen des Reaktionsprodukts mit wss. H2SO4 2: 130 - 135 °C / unter Druck View Scheme
参考文献
Ettel; Neumann
Collection of Czechoslovak Chemical Communications, 1958 , vol. 23, p. 1319
反应条件
ammonia in ethylene glycol
T=150 - 160°C; 1 h;
参考文献
Del Giudice, Maria Rosaria; Borioni, Anna; Mustazza, Carlo; Gatta, Franco
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 6 p. 1661 - 1667
参考文献
Bindra, Jasjit S.; Rastogi, Shri Nivas; Patnaik, G. K.; Anand, N.; Rao, K. G. Gurudath; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 318 - 329
